112697-90-2Relevant academic research and scientific papers
An efficient synthesis and antibacterial screening of novel oxazepine α-aminophosphonates by ultrasound approach
Sonar, Swapnil S.,Sadaphal, Sandip A.,Labade, Vilas B.,Shingate, Bapurao B.,Shingare, Murlidhar S.
, p. 65 - 73 (2010)
An efficient synthesis of novel -aminophosphonates by the reaction of quino[2,3-b][1,5]benzoxazepines with triethyl phosphite in the presence of the easily available, inexpensive, and nontoxic catalyst p-toluene sulphonic acid (p-TSA). This method affords the -aminophosphonates under the influence of ultrasound irradiation in solvent-free conditions, in short reaction times (4-6 min), high yields (80-90%), with improved purity. The synthesized -aminophosphonates show antibacterial activity against Gram-positive and Gram-negative bacteria. Supplemental materials are available for this article. Go to the publisher′s online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.
SYNTHESIS OF QUINOBENZOXAZEPINES: A NOVEL TETRACYCLIC RING SYSTEM
Zecchini, Giampiero Pagani,Torrini, Ines,Paradisi, Mario Paglialunga
, p. 2443 - 2447 (2007/10/02)
The one-pot synthesis of quinobenzoxazepines 3a-c from 2-chloroquinoline-3-carbaldehydes 1a-c and ortho-aminophenol is described.Reduction of 3a-c with lithium aluminum hydride afforded 11,12-dihydroquinobenzoxazepines 4a-c in high
