1127-01-1

Basic information

• Product Name: ETHYL 1-HYDROXYCYCLOHEXANE-CARBOXYLATE
• Synonyms: ETHYL 1-HYDROXYCYCLOHEXANE-CARBOXYLATE;Ethyl-1-hydroxycyclohexylacetate;1-Hydroxycyclohexanecarboxylic acid ethyl ester;Ethyl 1-hydroxycyclohexane-1-carboxylate;NSC 7384
• CAS NO: 1127-01-1
• Molecular Formula: C₉H₁₆O₃
• Molecular Weight: 172.22
• EINECS: 201-215-5
• Product Categories: Cycloalkanes
• Mol File: 1127-01-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 228℃
• Flash Point: 86℃
• Appearance: /
• Density: 1.104
• Vapor Pressure: 0.0147mmHg at 25°C
• Refractive Index: 1.4532
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.28±0.20(Predicted)
• CAS DataBase Reference: ETHYL 1-HYDROXYCYCLOHEXANE-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 1-HYDROXYCYCLOHEXANE-CARBOXYLATE(1127-01-1)
• EPA Substance Registry System: ETHYL 1-HYDROXYCYCLOHEXANE-CARBOXYLATE(1127-01-1)

Safety Data

• Hazardous Substances Data: 1127-01-1(Hazardous Substances Data)

Usage

General Description

Ethyl 1-Hydroxycyclohexane Carboxylate is a chemical compound with the molecular formula C9H16O3. This organic compound belongs to the family of cyclohexanecarboxylic acids and derivatives. Its systematic name is Ethyl (1-hydroxycyclohexyl)acetate. It exists as a colorless liquid at room temperature, and is typically utilized in a variety of chemical reactions due to its reactive nature. It is not widely produced or used, and details about its risk or safety profiles are not easily available, suggesting it is generally applied in more specialized or limited-scale industrial chemistry settings.

InChI:InChI=1/C9H16O3/c1-2-12-8(10)9(11)6-4-3-5-7-9/h11H,2-7H2,1H3

Upstream product

• 1123-28-0 1-hydroxy-cyclohexanecarboxylic acid 
• 64-17-5 ethanol 
• 931-97-5 1-hydroxy-1-cyclohexanecarbonitrile 
• 108-94-1 cyclohexanone 
• 3289-28-9 ethyl cyclohexanecarboxylate 

Downstream Products

• 7759-32-2 5,5-Pentamethylenoxazolidin-2,4-dion 
• 136786-44-2 1-(3-{(1S,2S,4aS,5S,6S,8S,8aR)-2-[(E)-3-(4-Methoxy-benzyloxy)-1-methyl-propenyl]-5-methoxymethoxy-1,6,8-trimethyl-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl}-3-oxo-propionyloxy)-cyclohexanecarboxylic acid methyl ester 
• 15753-47-6 1-(hydroxymethyl)cyclohexanol 
• 1617-22-7 cyclohex-1-enecarboxylic acid ethyl ester 
• 148476-22-6 3-(2,4-dichlorophenyl)-4-hydroxy-1-oxaspiro[4.5]dec-3-en-2-one 
• 148477-71-8 spirodiclofen 
• 591-48-0 3-Methyl-cyclohexene 
• 636-82-8 cyclohexene-1-carboxylic acid 
• 3289-28-9 ethyl cyclohexanecarboxylate 
• 57865-45-9 1-acetoxy-cyclohexanecarboxylic acid ethyl ester 
• 1513864-32-8 C₁₆H₂₀O₄ 
• 1513864-34-0 C₁₄H₂₄O₄ 
• 1031387-08-2 C₂₄H₂₇FO₄ 
• 1031387-04-8 C₂₅H₂₅FO₅ 

Relevant articles and documents

Production process of high-purity and high-yield spirodiclofen

The invention relates to the technical field of synthesis of compounds and specifically relates to a production process of high-purity and high-yield spirodiclofen. The production process comprises the following steps: performing an addition reaction on cyclohexanone which is taken as a starting material, so as to obtain 1-cyano-cyclohexanol; hydrolyzing and esterifying the 1-cyano-cyclohexanol, so as to obtain 1-hydroxylethyl formate; performing a condensation ring-closing reaction on the 1-hydroxylethyl formate, so as to obtain an intermediate caproate; and performing a reaction on the caproate and 2, 2-dimethylbutyryl chloride, so as to obtain the spirodiclofen. According to the production process, the problem in the prior art that the prepared spirodiclofen is low in purity and yield is solved; the spirodiclofen prepared by adopting the production process is high in purity and yield; and in addition, the raw material for preparing the spirodiclofen is easily obtained, and the operation is convenient.

Spirodiclofen and spiromesifen - Novel acaricidal and insecticidal tetronic acid derivatives with a new mode of action

The broad spectrum acaricides spirodiclofen (BAJ2740, trade name: Envidor) and spiromesifen (BSN2060, trade name: Oberon) with an additional excellent activity against whiteflies, both belong to the new chemical class of tetronic acid derivatives discovered at Bayer CropScience during the 1990s. The discovery process starting from herbicidal PPO (protoporphyrinogen oxidase) chemistry, the synthetic routes leading to the products, and some insight into process development of central intermediates is given. Spirodiclofen and spiromesifen have a new mode of action (interference with lipid biosynthesis), show no cross-resistance to any resistant mite or whitefly field population and are therefore valuable tools for resistance management.