112711-35-0Relevant articles and documents
Total Synthesis and Biological Evaluation of the Glycosylated Macrocyclic Antibiotic Mangrolide A
Hattori, Hiromu,Roesslein, Joel,Caspers, Patrick,Zerbe, Katja,Miyatake-Ondozabal, Hideki,Ritz, Daniel,Rueedi, Georg,Gademann, Karl
supporting information, p. 11020 - 11024 (2018/07/31)
The macrocyclic antibiotic mangrolide A has been described to exhibit potent activity against a number of clinically important Gram-negative pathogens. Reported is the first enantioselective total synthesis of mangrolide A and derivatives. Salient features of this synthesis include a highly convergent macrocycle preparation, stereoselective synthesis of the disaccharide moiety, and two β-selective glycosylations. The synthesis of mangrolide A and its analogues enabled the re-examination of its activity against bacterial pathogens, and only minimal activity was observed.
Tetrabutylammonium nitrite - acetic anhydride system, tetrabutylammonium nitrite, tetrabutylammonium acetate, and cesium acetate - 18-crown-6 for efficient unmasking of alkyl N-phenylcarbamates
Akai, Shoji,Nishino, Noriaki,Iwata, Yukihiro,Hiyama, Jun-Ichi,Kawashima, Etsuko,Sato, Ken-Ichi,Ishido, Yoshiharu
, p. 5583 - 5586 (2007/10/03)
Novel unmasking procedures for alkyl N-phenylcarbamates are established by the use of a tetrabutylammonium nitrite (Bu4NNO2) - acetic anhydride system, Bu4NNO2, Bu4NOAc, and CsOAc 18-crown-6 towards variously functionalized sugar derivatives.
Stereospecific synthesis of branched-chain sugars by a novel aldol-type cyclocondensation
Perez-Perez, Maria-Jesus,Camarasa, Maria-Jose,Diaz-Ortiz, Angel,Felix, Ana San,Heras, Federico G. de las
, p. 399 - 411 (2007/10/02)
A procedure for the preparation of branched-chain sugars having highly functionalised C-branches is reported.Reaction of furanos-3-uloses, pyranos-3-uloses, or pyranos-2-uloses with sodium cyanide followed by mesylation of the corresponding cyanohydrin af