112741-25-0

Upstream product

• 112741-47-6 tert-Butyl-[(1S,2R,3aS,6aS)-5-[2-methoxy-eth-(E)-ylidene]-2-(tetrahydro-pyran-2-yloxy)-octahydro-pentalen-1-ylmethoxy]-dimethyl-silane 
• 2043-61-0 cyclohexanecarbaldehyde 
• 112763-20-9 tert-Butyl-[(1S,2R,3aS,6aS)-5-((E)-2-methoxy-vinyl)-2-(tetrahydro-pyran-2-yloxy)-1,2,3,3a,6,6a-hexahydro-pentalen-1-ylmethoxy]-dimethyl-silane 
• 81060-37-9 (cyclohexylcarbonyl)dibromomethane 
• 92134-25-3 (1R,5S,6S,7R)-6-tert-butyldimethylsilyloxymethyl-7-tetrahydropyranyloxybicyclo<3.3.0>oct-2-ene-3-carbaldehyde 

Downstream Products

• 112741-38-5 (E)-1-Cyclohexyl-3-[(1R,2R,3aS,6aS)-5-[2-methoxy-eth-(E)-ylidene]-2-(tetrahydro-pyran-2-yloxy)-octahydro-pentalen-1-yl]-propenone 
• 120294-28-2 (Z)-2-Bromo-1-cyclohexyl-3-[(1S,2R,3aS,6aS)-5-[2-methoxy-eth-(E)-ylidene]-2-(tetrahydro-pyran-2-yloxy)-octahydro-pentalen-1-yl]-propenone 

Relevant academic research and scientific papers

A New Method for the Introduction of Carbon-Carbon Triple Bond at C-13 in PG Synthesis. A Stereocontrolled Synthesis of ZK 96 480

ZK 96 480, a chemically and metabolically stable prostacyclin analogue, has been synthesized from the Corey lactone in a stereocontrolled manner by a route utilizing a newlyeveloped method for introduction of the carbon-carbon triple bond at C-13 (PG numb