1127562-54-2Relevant academic research and scientific papers
A novel microwave-irradiated solvent-free 3-acylation of indoles on alumina
Lai, Qiu Yu,Liao, Rong Su,Wu, Shao Yong,Zhang, Jia Xin,Duan, Xin Hong
, p. 4069 - 4076 (2013)
A simple and efficient 3-acylation of indoles under microwave-heated and solvent-free conditions is developed. This general procedure uses neutral Al2O3 as a new, green and reusable catalyst giving good to high yields within short reaction times. Utilizing such an environmentally- benign methodology, a variety of indoles bearing electron-releasing or electron-withdrawing groups were conveniently acylated.
Site-Selective Addition of Maleimide to Indole at the C-2 Position: Ru(II)-Catalyzed C-H Activation
Lanke, Veeranjaneyulu,Bettadapur, Kiran R.,Prabhu, Kandikere Ramaiah
, p. 4662 - 4665 (2015)
Synthesis of 3-(indol-2-yl)succinimide derivatives is presented using a directing group strategy. Selective functionalization of C-2 in the presence of highly reactive C-3 in indole derivatives has been achieved. A conjugate addition product instead of He
Highly regioselective C2-alkenylation of indoles Uusing the N-benzoyl directing group: An efficient Ru-catalyzed coupling reaction
Lanke, Veeranjaneyulu,Prabhu, Kandikere Ramaiah
supporting information, p. 2818 - 2821 (2013/07/19)
A highly regioselective alkenylation of indole at the C2-position has been achieved using the Ru(II) catalyst by employing a directing group strategy. This strategy offers rare selectivity for the alkenylation N-benzoylindole at the C-2 position in the pr
