112758-77-7Relevant academic research and scientific papers
The effect of lipophilic substituents on the H2-histaminergic activity of some close analogues of impromidine
Sellier,Elz,Buschauer,Schunack
, p. 471 - 476 (1992)
The cimetidine-like moiety of the potent H2-agonist impromidine (9a) and three closely related guanidines (10a, 11a, and 12a) which are modified in the imidazolylpropyl portion, has been replaced by 2-[(2-pyridyl)methylthio]ethyl, 2-(benzylthio
Synthesis and pharmacological activity of arylmethylthioethylguanidines
Buschauer
, p. 1008 - 1012 (2007/10/02)
Impromidine analogues guanidines have been prepared characterized by H2-unspecific arylmethyl groups instead of the 5-methylimidazole residue. The most potent substances proved to be about 20 times more active than histamine at the isolated spo
