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112777-75-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 112777-75-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,7,7 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 112777-75:
130 % 10 = 0
So 112777-75-0 is a valid CAS Registry Number.

112777-75-0Relevant articles and documents

Chemical assembly systems: Layered control for divergent, continuous, multistep syntheses of active pharmaceutical ingredients

Ghislieri, Diego,Gilmore, Kerry,Seeberger, Peter H.

supporting information, p. 678 - 682 (2015/03/04)

While continuous chemical processes have attracted both academic and industrial interest, virtually all active pharmaceutical ingredients (APIs) are still produced by using multiple distinct batch processes. To date, methods for the divergent multistep continuous production of customizable small molecules are not available. A chemical assembly system was developed, in which flow-reaction modules are linked together in an interchangeable fashion to give access to a wide breadth of chemical space. Control at three different levels - choice of starting material, reagent, or order of reaction modules - enables the synthesis of five APIs that represent three different structural classes (γ-amino acids, γ-lactams, β-amino acids), including the blockbuster drugs Lyrica and Gabapentin, in good overall yields (49-75%).

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