112800-92-7Relevant academic research and scientific papers
Synthesis of TriazoloTriazinoindole Derivatives and 3-Substituted 5-Ethyl-H-1,2,4-triazinoindole
Younes, Mansour I.,Abdel-Alim, Alim M.,Abbas, Hessan H.,Metwally, Saoud A.
, p. 1196 - 1202 (2007/10/02)
5-Ethyl-3-hydrazino-5H-1,2,4-triazinoindole (2) reacts with aromatic aldehydes in anhydrous ethanol to yield substituted arylidene-(5-ethyl-5H-1,2,4-triazinoindol-3-yl)hydrazones 3.Treatment of 3 with excess SOCl2 gave 10-ethyl-1-aryl-10H-triazolotriazinoindoles 4, while the reaction of 2 with CS2 in methanolic KOH afforded 10-ethyl-2,10-dihydro-1H-triazolotriazinoindol-1-thione (5).Fusion of 1 with aromatic amines leads to 3-(arylamino)-5-ethyl-5H-1,2,4-triazinoindoles 6, whereas the reaction of 1 with alkyl or aralkyl halides in anhydrous acetone and in the presence of anhydrous K2CO3 results in the alkylation of the thiol group to give the alkylthio or aralkylthio derivatives 7.
