112815-99-3Relevant academic research and scientific papers
Process for making substituted pyrazoles
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Example 84, (2010/01/30)
This invention relates to a novel process of preparing selected 5-substituted pyrazoles useful as p38 kinase and COX-2 inhibitors.
SYNTHESES OF 1-PHENYL-2-(4-PYRIMIDINYL)ETHANONE AND RELATED ETHANONES.
Sund,Strickland
, p. 216 - 217 (2007/10/02)
Eleven 1-phenyl-2-(4-pyrimidinyl)ethanones were synthesized by the condensation of 4-methylpyrimidine and the requisite methyl benzoate ester with sodium hydride as the condensing agent. Substituents in the 3-and 4-position of the phenyl ring were chloro, dimethylamino, methoxy, methyl, and trifluoromethyl.
