Welcome to LookChem.com Sign In|Join Free

CAS

  • or

112875-61-3

Post Buying Request

112875-61-3 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • Manufacture Calcipotriol Intermediate (1alpha,3beta,5Z,7E,22E,24S)-24-Cyclopropyl-1,3-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-9,10-secochola-5,7,10(19),22-tetraen-24-ol

    Cas No: 112875-61-3

  • No Data

  • 10 Gram

  • 10 Kilogram/Month

  • Hangzhou Think Chemical Co. Ltd
  • Contact Supplier
  • (1S,4R,E)-4-((1R,3aS,7aR,E)-4-((Z)-2-((3S,5R)-3,5-bis((tert-butyldiMethylsilyl)oxy)-2-Methylenecyclohexylidene)ethylidene)-7a-Methyloctahydro-1H-inden-1-yl)-1-cyclopropylpent-2-en-1-ol

    Cas No: 112875-61-3

  • No Data

  • No Data

  • No Data

  • ZHEJIANG JIUZHOU CHEM CO.,LTD
  • Contact Supplier

112875-61-3 Usage

Uses

1,3-Bis(O-TBDMS)-Calcipotriene is the tert-Butyldimethylsilyl ether conjugate of Calcipotriene (C144200), a vitamin D3 analogue with potential antitumor activities.

Check Digit Verification of cas no

The CAS Registry Mumber 112875-61-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,8,7 and 5 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 112875-61:
(8*1)+(7*1)+(6*2)+(5*8)+(4*7)+(3*5)+(2*6)+(1*1)=123
123 % 10 = 3
So 112875-61-3 is a valid CAS Registry Number.

112875-61-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (E,1S,4R)-4-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-1-cyclopropylpent-2-en-1-ol

1.2 Other means of identification

Product number -
Other names 1,3-Bis-O-(tert-butyldimethylsilyl)calcipotriene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:112875-61-3 SDS

112875-61-3Downstream Products

112875-61-3Relevant articles and documents

Stereoselective synthesis of C24-hydroxylated vitamin D3 analogs: A practical and expeditius route to calcipotriol

Rumbo, Antonio,Perez-Garcia, Xenxo,Mourino, Antonio

scheme or table, p. 68 - 70 (2011/11/14)

The synthesis of the clinically important drug calcipotriol (2, MC903) is described as an example of a new and efficient approach to C24-hydroxylated analogs and metabolites of vitamin D3 (1). The key step of the process is the generation of the C24 stereocenter by DAIB [(-)-3-exo-(dimethylamino)isoborneol]-catalyzed addition of the alkenylzinc derivative of alkyne 3 to cyclopropylcarboxaldehyde.

ISOMERISATION OF PHARMACEUTICAL INTERMEDIATES

-

Page/Page column 21-22, (2008/06/13)

The present invention relates to an isomerisation method of vitamin D analogues, such as compounds useful for the synthesis of calcipotriol, and to and to the use of a flow- through photoreactor or continuous flow photoreactor reactor for making said vitamin D analogues. The present invention relates further to the use of intermediates produced with said method for making calcipotriol or calcipotriol monohydrate, or pharmaceutical formulations thereof.

STEREOSELECTIVE SYNTHESIS OF VITAMIN D ANALOGUES

-

Page/Page column 31, (2008/06/13)

The present invention relates to intermediates useful for the synthesis of calcipotriol or calcipotriol monohydrate, to methods of producing said intermediates, and to methods of stereoselectively reducing said intermediates.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 112875-61-3