1129-25-5

Usage

Uses

Used in Organic Synthesis:
4-(methylthio)benzenesulfonyl chloride(SALTDATA: FREE) is used as a reagent for the introduction of the sulfonyl group into various organic compounds, facilitating the synthesis of a wide range of chemical products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-(methylthio)benzenesulfonyl chloride(SALTDATA: FREE) is used as an intermediate in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and therapeutic agents.
Used in Chemical Research:
4-(methylthio)benzenesulfonyl chloride(SALTDATA: FREE) is utilized as a research tool in chemical laboratories for studying the reactivity and properties of sulfonyl chloride compounds, aiding in the advancement of chemical knowledge and the discovery of novel applications.

InChI:InChI=1/C7H7ClO2S2/c1-11-6-2-4-7(5-3-6)12(8,9)10/h2-5H,1H3

Upstream product

• 100-68-5 methyl-phenyl-thioether 

Downstream Products

• 82964-91-8 4-methylsulfinylbenzenesulfonyl chloride 
• 1122-97-0 4-methylsulfanyl-thiophenol 
• 20057-77-6 1,2-bis[4-(methylthio)phenyl]disulfane 
• 333987-42-1 1-tert-Butoxycarbonyl-4-{ethyl[4-(methylsulfanyl)phenylsulfonyl]amino}piperidine 
• 235427-42-6 2-(3-chloro-5-pyridyloxy)-5-(4-methylthiobenzenesulfonamido)benzotrifluoride 
• 1252015-28-3 2-[(4-methylthio)benzenesulfonyl]-1-methyl-3-ethoxypropane-1,3-dione 
• 1252015-27-2 2-[(4-methylthio)benzenesulfonyl]-1,3-diphenylpropane-1,3-dione 
• 1352051-26-3 2-[(4-methylthio)benzenesulfonyl]-1,3-dimethylpropane-1,3-dione 
• 1252015-25-0 2-[(4-methylthio)benzenesulfonyl]-1-methyl-3-phenylpropane-1,3-dione 
• 1352051-27-4 6-[(4-methylthio)benzenesulfonyl]-5,7-dimethyl-2,3-dihydro-1H-1,4-diazepine 
• 1352051-28-5 6-[(4-methylthio)benzenesulfonyl]-5-methyl-7-phenyl-2,3-dihydro-1H-1,4-diazepine 
• 1352051-29-6 6-[(4-methylthio)benzenesulfonyl]-5,7-diphenyl-2,3-dihydro-1H-1,4-diazepine 
• 1352051-30-9 6-[(4-methylthio)benzenesulfonyl]-7-methyl-2,3,4,6-tetrahydro-1H-1,4-diazepine-5-one 
• 1352051-31-0 3-[(4-methylthio)benzenesulfonyl]-2,4-dimethyl-3H-1,5-benzodiazepine 

Relevant academic research and scientific papers

Spectra, Ionization Constants, and Rates of Oxidation of 1,4-Dimercaptobenzene and Properties of the p-Mercaptophenylthiyl and p-Benzodithiyl Anion Radicals

In basic solution, p-dimercaptobenzene, which is found to have pKa's of 6.0 and 7.7, is rapidly oxidized by azide radical (k = 7.4*109 M-1 s-1) to p-benzodithiyl radical anion, the sulfur analog of p-benzosemiqu

Silica sulfuric acid as a mild and efficient reagent for the synthesis of 1,4-Diazepine and 1,5-Benzodiazepine derivatives

The synthesis of biologically active 1H-1,4-diazepines 4a-d and 3H-1,5-benzodiazepines 5a-d in good yields, from the heterocyclization reaction of 2-(4-methylthio benzenesulfonyl)-1,3-dimethyl/1-methyl-3-phenyl/1,3-diphenyl/ 1-methyl-3- ethoxy propane-1,3

NEW ADAMANTANE DERIVATIVES AS DIPEPTIDYL, PEPTIDASE IV INHIBITORS, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

The present invention relates to dipeptidyl peptidase IV (DPP-IV) inhibitors of the formula (A): wherein R1, R2, Y, and n are as defined herein, pharmaceutical compositions containing the same, processes for their preparation, and methods for treating disorders mediated by DPP-IV inhibition, such as diabetes, especially Type II diabetes, with them.

NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM

The present invention relates to novel organic compounds, more particularly, novel Dipeptidyl peptidase IV (DPP-IV) inhibitors of general formula (I) wherein: Y is -S(O)m-, -CH2-, -CHF-, or -CF2; X and Z are independently -C(=O)-, -NR3-, - O- or -S(O)m-; each occurrence of m is independently 0, 1 or 2; a is 0, 1 or 2; b is 0, 1 or 2; the dotted line [----] in the carbocyclic ring represents an optional double bond; R1 is substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkylalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocyclic ring, substituted or unsubstituted heterocyclylalkyl, or substituted or unsubstituted heteroarylalkyl; R2 is hydrogene, nitrile (-CN), COOH, or an isostere of carboxylic; or analogs, tautomers, enantiomers, diastereomers, regioisomers, stereoisomers, polymorphs, pharmaceutically acceptable salts, N-oxides, pharmaceutically acceptable solvates and pharmaceutical compositions containing them.

Method of producing bis(4-alkylthiophenyl) disulfides

The present invention relates to a method of producing bis(4-alkylthiophenyl) disulfides characterized by (a) reducing directly a 4-alkylthiobenzenesulfonyl chloride, or (b) oxidizing a 4-alkylthiobenzenethiol obtained by reducing a 4-alkylthiobenzenesulfonyl chloride. The present invention is capable of producing the compound below useful as an intermediate of pharmaceuticals. STR1