112914-08-6

Basic information

• Product Name: 2-(4-benzylMorpholin-2-yl)ethan-1-aMine
• Synonyms: 2-(4-benzylMorpholin-2-yl)ethan-1-aMine;2-(4-Benzylmorpholin-2-yl)ethanamine;4-Benzyl-2-morpholineethanamine
• CAS NO: 112914-08-6
• Molecular Formula: C₁₃H₂₀N₂O
• Molecular Weight: 220.3107
• Mol File: 112914-08-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 327.9±22.0 °C(Predicted)
• Appearance: /
• Density: 1.058±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 9.90±0.10(Predicted)
• CAS DataBase Reference: 2-(4-benzylMorpholin-2-yl)ethan-1-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-benzylMorpholin-2-yl)ethan-1-aMine(112914-08-6)
• EPA Substance Registry System: 2-(4-benzylMorpholin-2-yl)ethan-1-aMine(112914-08-6)

Safety Data

• Hazardous Substances Data: 112914-08-6(Hazardous Substances Data)

Usage

Chemical class

amines and morpholine derivatives

Type of amine

tertiary amine

Structural components

benzyl group and morpholine ring attached to an ethylamine backbone

Use in organic synthesis and pharmaceutical research

as a building block for the synthesis of various bioactive molecules and pharmaceuticals

Potential applications

medicinal chemistry, drug discovery, and development of new therapeutic agents for various diseases and conditions.

Upstream product

• 57962-45-5 (4-benzylmorpholin-2-yl)acetonitrile 
• 110-16-7 maleic acid 
• 104-63-2 N-Benzylethanolamine 
• 73933-19-4 ethyl 4-(phenylmethyl)-2-morpholineacetate 
• 40987-25-5 N-benzyl-2-chloromethylmorpholine 
• 122894-54-6 2-(2-chloroethyl)-4-(phenylmethyl)morpholine 
• 112887-43-1 2-(2-hydroxyethyl)-4-benzylmorpholine 
• 126645-72-5 N-<2-(4-benzyl-2-morpholinyl)ethyl>phthalimide 

Downstream Products

• 126645-69-0 4-amino-N-[2-(4-benzyl-2-morpholinyl)ethyl]-5-chloro-2-ethoxybenzamide 
• 126645-68-9 4-amino-N-[2-(4-benzyl-2-morpholinyl)ethyl]-5-chloro-2-methoxybenzamide 
• 1099048-31-3 N-[2-(4-Benzyl-2-morpholinyl)ethyl]-5-(1,2-dithiolan-3-yl)pentane Thioamide 
• 627860-53-1 C₁₅H₁₉F₃N₂O₂ 

Relevant articles and documents

Quinolone antimicrobial agents substituted with morpholines at the 7- position. Syntheses and structure-activity relationships

A series of novel 7-substituted 1-cyclopropyl-6,8-difluoro-1,4-dihydro-4- oxo-3-quinolinecarboxylic acids have been prepared and tested for antibacterial activities and for convulsive activities in combination with nonsteroidal antiinflammatory drug. Stru

Substituted benzamide derivatives, for enhancing gastrointestinal motility

Compounds of the formula: STR1 wherein R is hydrogen, alkoxycarbonyl, benzyloxycarbonyl, heteroarylalkyl, phenylalkenyl, or --T--(Y)p --R6 (wherein T is single bond or alkylene, Y is oxygen, sulfur or carbonyl, R6 is phenyl, substituted phenyl, naphthyl, or diphenylmethyl, and p is 0 or 1, provided that when T is single bond, p is 0); R1 is halogen, hydroxy, alkoxy, cycloalkyloxy, alkenyloxy, alkynyloxy, alkoxy interrupted by oxygen or carbonyl, alkylthio, amino, monosubstituted amino, or a substituted alkoxy; R2 is hydrogen; R3 is hydrogen, halogen, amino, alkylamino, dialkylamino, alkanoylamino, or nitro; R4 is hydrogen, halogen, nitro, sulfamoyl, alkylsulfamoyl, or dialkylsulfamoyl; or any two adjacent groups of the R1, R2, R3 and R4 may combine to form alkylenedioxy, and the remaining two groups are each hydrogen; R5 is hydrogen or alkyl; X is alkylene; m and n are each 1 or 2; provided that at least one of the groups R2, R3 and R4 is other than hydrogen, and acid addition salts, quaternary ammonium salts and N-oxide derivatives thereof, processes for preparation thereof, and pharmaceutical composition containing the same. Said compounds, salts and N-oxide derivatives thereof show excellent gastrointestinal motility enhancing activity.