112916-65-1

Upstream product

• 112918-01-1 2-endo-(carbomethoxymethyl)-3-endo-carboxybicyclo<2.2.1>heptane 
• 125109-72-0 (1S,2S,6R,7R)-4-Hydroxy-3-aza-tricyclo[5.2.1.0^2,6]decane-3-carboxylic acid benzyl ester 
• 43000-60-8 2-endo-(carboxymethyl)-3-endo-carboxybicyclo<2.2.1>heptane 
• 2825-86-7 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-indene 
• 186581-53-3 diazomethane 
• 142646-81-9 (Z)-7-((1S,2S,3R,4R)-3-Benzyloxycarbonylamino-bicyclo[2.2.1]hept-2-yl)-hept-5-enoic acid 

Downstream Products

• 112916-81-1 (5Z)-7-<3-endo-<(phenylsulfonyl)amino>bicyclo<2.2.1>hept-2-endo-yl>heptenoic acid methyl ester 
• 112916-68-4 (5Z)-7-<3-endo-<(phenylsulfonyl)amino>bicyclo<2.2.1>hept-2-endo-yl>heptenoic acid 

Relevant academic research and scientific papers

Synthesis and in vitro activity of stereoisomers of a novel thromboxane receptor antagonist, (±)-(5Z)-7-[3-endo-[(phenylsulfonyl)amino]bicyclo[2.2.1]hept-2-exo-yl ]heptenoic acid

Three stereoisomers of S-145 (1) with variations at the side-chain junctions were synthesized. Endo-cis-isomer 10 and N-exo-trans isomer 18 were obtained via the common intermediate 5 having an endo-fused ring structure. Exo-cis isomer 28 was prepared via