112919-52-5

Upstream product

• 112919-48-9 4-methyl-7,8,10,11-tetraazaspiro<5,5>undecane-9-thione 
• 79-11-8 chloroacetic acid 
• 589-92-4 1-methylcyclohexan-4-one 

Downstream Products

• 112919-55-8 C₁₇H₁₉N₅O₃S 
• 112919-58-1 C₁₇H₂₀N₄O₂S 
• 112919-56-9 C₁₉H₂₄N₄O₃S 
• 115041-82-2 C₁₇H₁₉ClN₄OS 
• 112919-57-0 C₁₉H₂₅N₅OS 
• 112919-54-7 7'-(p-methoxybenzylidene)-4-methyl-6'(7'H)-oxospirothiazolo<3,2-b>-s-tetrazine> 
• 115041-83-3 C₁₇H₂₀N₄OS 
• 115041-81-1 C₁₇H₁₉ClN₄OS 

Relevant academic research and scientific papers

Heterocyclic Systems Containing Bridgehead Nitrogen Atom: Part LXI - Facile Synthesis of Spirothiazolo--s-tetrazine>, a New Heterocyclic System

9,10,12,13-Tetraazaspirotridecane-11-thione (IIc) and 4-methyl-7,8,10,11-tetraazaspiroundecane-9-thione (IIe) on reaction with chloroacetic acid yield 6'(7'H)-oxospirothiazolo-s-tetrazine (IIIc) and 4-methyl-6'(7

Heterocyclic Systems Containing Bridgehead Nitrogen Atom: Synthesis and Antimicrobial Activities of Spiro-thiazolo-s-tetrazine> Analogs

Synthesis of the spiro-thiazolo-s-tetrazine>analogs IIa, b, c and e has been achieved in a single step by treating 1,2,4,5-tetraazaspiroundecane-3-thione(Ia), 1,2,4,5-tetraazaspirododecane-3-thione (Ib), 1,2,4,5-tetraazaspirotridecane-3-thione (Ic) and 9-methyl-1,2,4,5-tetraazaspiroundecane-3-thione (Id) respectively with α-bromopropionic acid.The reaction of Id with chloroacetic acid results in the facile synthesis of 4-methyl-6'(7'H)-oxospiro-thiazolo-s-tetrazine> (IId). 7-Arylidene derivatives (III) have been prepared by condensation of IId with ald ehydes as well as by reaction of Id with ethyl chloroacetate and aldehydes in a single step.The structures II and III have been established by IR and PMR spectral data.The antibacterial and antifungal activities of II and III have been determined.