1129210-40-7Relevant academic research and scientific papers
Second generation 4-(4-methyl-1H-indol-5-ylamino)-2-phenylthieno[2,3-b]pyridine-5-carbonit rile PKCθ inhibitors
Wu, Biqi,Boschelli, Diane H.,Lee, Julie,Yang, Xiaoke,Chaudhary, Divya
, p. 766 - 769 (2009)
Thieno[2,3-b]pyridine-5-carbonitrile 16 with a 4-methyl-5-indolylamine at C-4 and a 5-methoxy-2-(dimethylamino)-methylphenyl group at C-2 had an IC50 value of 16 nM for the inhibition of PKCθ. While moderate inhibition of PKCδ was also observed
