1129399-27-4Relevant academic research and scientific papers
Asymmetric desymmetrization of the diallyl acetals of alkynals by the enantioselective Pauson-Khand-type reaction catalysts
Dong, Eun Kim,Bo, Hyung Lee,Rajagopalasarma, Mudigonda,Genet, Jean-Pierre,Ratovelomanana-Vidal, Virginie,Jeong, Nakcheol
supporting information; experimental part, p. 2695 - 2700 (2009/10/14)
Asymmetric desymmetrization of the di-allyl acetals of alkynal (1) by an enantioselective Pauson-Khand-type reaction catalyst was studied. The corresponding 5-oxabicyclo[3.3.0]octenones (2) were obtained as a mixture of diastereomers (2a and 2b), which were hydrolyzed to afford a single enantiomer (3), in high yields (up to 88%) as well as excellent enantioselectivities (up to 97%).
