1129540-60-8

Upstream product

• 1129541-42-9 4-methoxy-N-(4-(3-methyl-1H-1,2,4-triazol-1-yl)phenyl)pyrimidin-2-amine 
• 52739-51-2 4-(3-methyl-1H-1,2,4-triazol-1-yl)aniline 

Downstream Products

• 1128097-83-5 4-(3,5-dichlorophenyl)-N-(4-(3-methyl-1H-1,2,4-triazol-1-yl)phenyl)pyrimidin-2-amine 
• 1129540-62-0 N-(4-(3-methyl-1H-1,2,4-triazol-1-yl)phenyl)-4-(trimethylstannyl)pyrimidin-2-amine 
• 1309880-05-4 C₁₇H₁₆N₈ 
• 1309880-04-3 C₁₆H₁₄N₈ 

Relevant academic research and scientific papers

Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors

The design and synthesis of a novel series of c-jun N-terminal kinase (JNK) inhibitors is described. The development of the 4-(pyrazol-3-yl)-pyridine series was discovered from an earlier pyrimidine series of JNK inhibitors. Through the optimization of th

SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS

The present invention provides novel substituted pyrimidinyl-amines that are useful as inhibitors of protein kinases, especially c-Jun N-terminal kinases (JNK) and pharmaceutical compositions thereof and methods of using the same for treating conditions responsive to the inhibition of the JNK pathway.