1129541-42-9Relevant academic research and scientific papers
Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors
No?l, Romain,Shin, Youseung,Song, Xinyi,He, Yuanjun,Koenig, Marcel,Chen, Weimin,Ling, Yuan Yuan,Lin, Li,Ruiz, Claudia H.,Lograsso, Phil,Cameron, Michael D.,Duckett, Derek R.,Kamenecka, Theodore M.
scheme or table, p. 2732 - 2735 (2011/06/22)
The design and synthesis of a novel series of c-jun N-terminal kinase (JNK) inhibitors is described. The development of the 4-(pyrazol-3-yl)-pyridine series was discovered from an earlier pyrimidine series of JNK inhibitors. Through the optimization of th
SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS
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Page/Page column 66, (2009/04/25)
The present invention provides novel substituted pyrimidinyl-amines that are useful as inhibitors of protein kinases, especially c-Jun N-terminal kinases (JNK) and pharmaceutical compositions thereof and methods of using the same for treating conditions responsive to the inhibition of the JNK pathway.
