112968-89-5

Upstream product

• 106-41-2 4-bromo-phenol 
• 50586-80-6 toluene-4-sulfonic acid 2-(2-methoxyethoxy)ethyl ester 
• 80392-30-9 diethylene glycol methyl phenyl ether 
• 54149-17-6 2-bromoethyl 2-methoxyethyl ether 
• 111-77-3 2-(2-methoxyethoxy)ethyl alcohol 

Downstream Products

• 112968-90-8 1-(4-allylphenoxy)-5-methoxy-3-oxapentane 
• 1366602-62-1 2-(4-(2-(2-methoxyethoxy)ethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant academic research and scientific papers

A double branched photosensitive prodrug: Synthesis and characterization of light triggered drug release

A novel oNB based, double branched photosensitive prodrug 1, and a biphenyl counterpart 2 were designed and synthesized. Their photo-triggered drug release properties were studied by HPLC and UV-vis spectra. The isobestic points in UV-vis spectra of prodr

New highly soluble triarylamine-based materials as promising catholytes for redox flow batteries

A series of arylamines bearing oligoethylene glycol ether solubilizing moieties were designed and comprehensively evaluated as promising catholyte materials for non-aqueous redox flow batteries (RFBs). The triphenylamine core maintains the chemical stability of the radical cation, the ethylene glycol chains enhance the solubility up to complete miscibility with organic solvents, and the electron-withdrawing bromine substituents increase the redox potential of the compounds up to 0.61 Vvs.Ag/AgNO3. The best material showed 99% coulombic efficiency in combination with good stability in over 50 charge-discharge cycles in laboratory RFB cells. The designed triarylamine-based catholyte materials appear promising for the development of next-generation high-voltage and high-capacity RFBs.

Quantitative real time sensing reveals enhanced sensitivity of polar dendrimer thin films for plastic explosive taggants

A method of introducing pulses of analyte vapours has been developed to study the interactions of nitro-containing analytes with fluorescent sensing films. The quenching of the photoluminescence of thin dendrimer films by exposure to sub-saturation concen

Comparison of Oligo(ethylene oxide)-Substituted Posysiloxanes with Poly(ethylene glycol) as Stationary Phases for Capillary Chromatography

The gas chromatographic properties of a new oligo(ethylene oxide)-substituted (glyme) polysiloxane stationary phase and an 18-crown-6-substituted (crown) polysiloxane phase were compared to Carbowax 20M and a bonded poly(ethylene glycol) (Bondable PEG).The glyme polysiloxane was found to have an operational temperature range of 20-280 deg C and a selectivity similar to that of Carbowax 20M.The crown polysiloxane was found to have unique selectivity, partly because of the size and shape of the crown ether cavity and the structures of solute molecules.Selected applications including the analysis of alcohols, fused oils, and nitrogen heterocycles are demonstrated.

MORPHINAN DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN

The present invention relates to compounds and their use as ligands for mu opioid receptors. Also included are methods for preparing the compounds and pharmaceutical compositions containing the compounds. In one or more embodiments of the invention, a compound according to Formula I is provided: and pharmaceutically acceptable salts thereof, wherein R1-R11 are as described herein.

PDE 10a Inhibitors for the Treatment of Type II Diabetes

Disclosed are compounds, compositions and methods for treating Type II diabetes. Such compounds are represented by Formula (I) as follows: wherein R1, R2, L, and Q are defined herein.

Novel Water-Soluble Organosilane Compounds as a Radical Reducing Agent in Aqueous Media

The development of novel water-soluble organosilane compounds and their application to radical reactions in water medium have been studied. A series of novel organosilane compounds having hydrophilic groups, such as an ether group and a hydroxy group in the side chain to bear hydrophilicity, were synthesized by the reaction of trichlorosilane or tetrachlorosilane and Grignard reagents. The reactivities of these organosilane compounds were studied in the radical reduction of 2-bromoethyl phenyl ether in ethanol in the presence of triethylborane under aerobic conditions. The results showed that diarylsilane was the most effective among them. The radical reduction of alkyl and aryl halides with diarylsilane was applied to a reaction in aqueous media, which gave the corresponding reduction product in good yields. Thus, the present organosilanes are very useful for the reduction of water-soluble substrates, such as halo sugars in water.

SELECTIV BROMINATION OF THE AROMATIC RING IN ω-PHENYLPOLYOXAALKANES AND ALKANOLS IN MICELLES

The regioselecticity of bromination of ω-phenylpolyoxaalkanes and alkanols by bromine in aqueous solution of dodecyl sulfate (SDS) and aqueous solution of cetyltrimethylammonium bromide (CTAB) are shown to be related to the average orientation of substrate as indicated by 1H NMR studies.Thus ortho-bromination is promoted at higher concentrations of the surfactant relative to pure water.In contrast, at an equal ratio of the surfactant and substrate para-bromination is promoted.The results are discussed with respect to the average orientation of substrate in a micellar microenvironment and the formation of an ether-bromine comples as possible bromination agent.