112969-91-2

Basic information

• Product Name: 2-FURYL-2-THIAZOLYL KETONE
• Synonyms: 2-FURYL-2-THIAZOLYL KETONE;2-(2-FUROYL)THIAZOLE
• CAS NO: 112969-91-2
• Molecular Formula: C8H5NO2S
• Molecular Weight: 179.2
• Mol File: 112969-91-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-FURYL-2-THIAZOLYL KETONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FURYL-2-THIAZOLYL KETONE(112969-91-2)
• EPA Substance Registry System: 2-FURYL-2-THIAZOLYL KETONE(112969-91-2)

Safety Data

• Hazardous Substances Data: 112969-91-2(Hazardous Substances Data)

Upstream product

• 527-69-5 2-furancarbonyl chloride 
• 79265-30-8 2-(trimethylsilyl)thiazole 
• 112970-04-4 1,3-Thiazol-2-yl(2-furyl)methanol 
• 98-01-1 furfural 
• 288-47-1 1,3-thiazole 

Relevant articles and documents

DMAP-catalyzed regel-type direct C-2 (Hetero)aroylation of oxazoles and thiazoles derivatives with acid chlorides

A Regel-type transition-metal-free direct C-2 aroylation of (benzo)oxazoles, (benzo)thiazoles and 1,3,4-oxadiazoles with acid chlorides catalyzed by N,N-dimethyl-4-aminopyridine (DMAP) is described. This methodology is effective with several aroyl and het

Synthesis of (Trimethylsilyl)thiazoles and Reactions with Carbonyl Compounds. Selectivity Aspects and Synthetic Utility

Synthetic routes to all possible regioisomeric mono- and bis(trimethylsilyl)thiazoles as well as to the tris(trimethylsilyl) derivative via lithiation-silylation sequences of the thiazole ring followed by selective protodesilylation in some cases are described. (Trimethylsilyl)thiazoles serve as thiazolyl donor synthons upon reaction with carbonyl compounds (ketenes, acyl chlorides, aldehydes) for the preparation of mono- and bis-substituted thiazoles in very good yields.Carbodesilylation occurs more readily at the 2- than 5-position, whereas no reaction takes place at the 4-position.A mechanism via a thiazolium 2-ylide as an intermediate is suggested for the carbodesilylation at the 2-position.