112980-35-5

Basic information

• Product Name: 3(2H)-Benzofuranone, 2-[(3-chlorophenyl)methylene]-, (Z)-
• CAS NO: 112980-35-5
• Molecular Formula: C15H9ClO2
• Molecular Weight: 256.688
• Mol File: 112980-35-5.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 3(2H)-Benzofuranone, 2-[(3-chlorophenyl)methylene]-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Benzofuranone, 2-[(3-chlorophenyl)methylene]-, (Z)-(112980-35-5)
• EPA Substance Registry System: 3(2H)-Benzofuranone, 2-[(3-chlorophenyl)methylene]-, (Z)-(112980-35-5)

Safety Data

• Hazardous Substances Data: 112980-35-5(Hazardous Substances Data)

Upstream product

• 108440-16-0 1-(2-hydroxyphenyl)-3-(3-chlorophenyl)prop-2-en-1-one 
• 118-93-4 o-hydroxyacetophenone 
• 587-04-2 m-Chlorobenzaldehyde 
• 73257-24-6 3-chlorophenylacetylene lithium 
• 119-36-8 methyl salicylate 
• 7169-34-8 3-oxo-2,3-dihydrobenzo[b]furan 

Relevant articles and documents

Transition-metal-free synthesis of polysubstituted pyrrole derivatives via cyclization of methyl isocyanoacetate with aurone analogues

Presented herein is an unprecedented transition-metal-free cyclization of methyl isocyanoacetate with aurone analogues catalyzed by NaOH. Various 2,3,4-trisubstituted pyrroles were obtained in excellent yields (up to 99%). The high efficiency of this synthetic procedure, coupled with the operational simplicity and atom economy, makes it an attractive method for the synthesis of polysubstituted pyrroles.

METHOD FOR SYNTHESIZING (Z)-AURONE AND DERIVATIVE COMPOUNDS THEREOF

One embodiment of the present invention is described below. Provided is (Z)-operon comprising o - (alkanone -1 - yl) phenol or its derivative compound in a thallium (Tl) catalyst and an cyclization step for cyclizing the compound under an organic solvent, and a method for producing the derivative compound.

Efficient Synthesis of (Z)-Aurones by the Thallium(I) acetate-Catalyzed 5-exo Cyclization of o-(Alkynon-1-yl)phenols

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