113027-08-0

Basic information

• Product Name: Ethanone, 1-[4-(1,1-dimethylethyl)-2-hydroxyphenyl]-
• CAS NO: 113027-08-0
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• Mol File: 113027-08-0.mol

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-(1,1-dimethylethyl)-2-hydroxyphenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-(1,1-dimethylethyl)-2-hydroxyphenyl]-(113027-08-0)
• EPA Substance Registry System: Ethanone, 1-[4-(1,1-dimethylethyl)-2-hydroxyphenyl]-(113027-08-0)

Safety Data

• Hazardous Substances Data: 113027-08-0(Hazardous Substances Data)

Upstream product

• 13189-51-0 3-(tert-butyl)phenyl acetate 
• 585-34-2 3-tert-butylphenyol 
• 64-19-7 acetic acid 
• 1206606-75-8 C₁₂H₁₇NO₂ 

Downstream Products

• 1206606-77-0 C₁₂H₁₈O₂ 
• 113027-10-4 4-(7-tert-Butyl-4-oxo-4H-chromen-2-yl)-benzoic acid methyl ester 

Relevant articles and documents

Catalytic direct C-acylation of phenol and naphthol derivatives using carboxylic acids as acylating reagents

Direct regioselective C-acylation of phenol and naphthol derivatives was carried out by using carboxylic acids as acylating reagents. The reactions proceeded smoothly in the presence of a catalytic amount of Hf(OTf)4 to afford the corresponding aromatic ketones in good yields.

O-acetyl oximes as transformable directing groups for Pd-catalyzed C-H bond functionalization

[Chemical equation presented] O-Acetyl oxlmes serve as effective directing groups for Pd-catalyzed sp2 and sp3 C-H functionalization reactions. The C-H functionalization products can be subsequently transformed Into ortho- or β-functionalized ketones, alcohols, amines, and heterocycles.

Antagonists of the Vanilloid Receptor Subtype 1 (VR1) and Uses Thereof

The present invention is directed to compounds of formula (I) wherein variables X1, X2, Y, R1a, R1b, R2a, R2b, A1, A2, A3, and A4 are as defined

Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor and uses thereof

Compounds that are antagonists of the VR1 receptor, having formula (I) [image] or a pharmaceutically acceptable salt, prodrug, or salt of a prodrug thereof, wherein A1, A2, A3, A4, R7, R8, R9, X, Y, Z, L, n, and m, are as defined herein, and are useful in disorders prevented or ameliorated by inhibiting the VR1 receptor.

The Catalytic Fries Rearrangement and o-Acylation Reactions Using Group 3 and 4 Metal Triflates as Catalysts

Group 3 and 4 metal triflates (Sc(OTf)3, TiCl(OTf)3, Zr(OTf)4, and Hf(OTf)4) were found to be efficient catalysts in the Fries rearrangement of phenyl or 1 -naphthyl acylates. It was also found that the o-acylation (direct acylation) reactions of phenols and 1-naphthols with acid chlorides proceeded smoothly in the presence of the triflates. Both reactions were successfully carried out using small amounts of the triflates (catalytically), and comparison of catalytic activities of these metal triflates in these reactions is discussed.

Hafnium trifluoromethanesulfonate (Hf(OTf)4) as an efficient catalyst in the Fries rearrangement and direct acylation of phenol and naphthol derivatives

Hafnium trifluoromethanesulfonate (hafnium triflate, Hf(OTf)4) was found to be an efficient catalyst in the Fries rearrangement of acyloxy benzene or naphthalene derivatives. The reactions proceeded smoothly in the presence of 5-20 mol% Hf(OTf)4. Regioselective direct acylation of phenol and naphthol derivatives with acid chlorides was also achieved by using Hf(OTf)4 as a catalyst.