1130893-75-2

Upstream product

• 66646-88-6 (E)-N-benzylideneglycine methyl ester 
• 1865-13-0 (Z)-β-phenylsulphonylacrylic acid methyl ester 

Downstream Products

• 1130894-78-8 (2R,3R,5S)-dimethyl 5-phenylpyrrolidine-2,3-dicarboxylate 
• 1130894-90-4 (2R, 5S)-dimethyl 2,5-dihydro-5-phenyl-1H-pyrrole-2,3-dicarboxylate 

Relevant academic research and scientific papers

The phenylsulfonyl group as a temporal regiochemical controller in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

(Chemical Equation Presented) Controlling the regioselectivity: The phenylsulfonyl group controlled the regioselectivity in the title reaction to afford pyrrolidine-2,3-dicarboxylates with good regioselectivity and high exo selectivity and enantioselectivity (see scheme). The products are precursors to substituted pyrrolidines and pyrrolines that are not attainable by direct 1,3-dipolar cycloadditions with typical acrylates.