1131-19-7Relevant academic research and scientific papers
Disulfide linked pyrazole derivatives inhibit phagocytosis of opsonized blood cells
Purohit, Meena K.,Scovell, Iain,Neschadim, Anton,Katsman, Yulia,Branch, Donald R.,Kotra, Lakshmi P.
supporting information, p. 2324 - 2327 (2013/05/09)
Immune thrombocytopenia (ITP) is caused by production of an autoantibody to autologous platelets. ITP can be treated either by reducing platelet destruction or by increasing platelet production. Fcγ receptor mediated phagocytosis of the opsonized blood ce
Preparation and Antibacterial Activity of 3-Methyl-1-p-substituted Phenylpyrazole-5-thiol
Tagawa, Yoshinobu,Minami, Shin'ichi,Yoshida, Toshio,Tanaka, Keitaro,Sato, Shuji,Goto, Yoshinobu,Yamagata, Kenji
, p. 99 - 103 (2007/10/03)
3-Methyl-1-phenylpyrazole-5-thiol (3a) and its p-nitro- (5) and p-fluorophenyl (8) derivatives were prepared as potential antimicrobial agents in relatively good yields. Compounds 3a and 8 showed good antibacterial activities against MRSA, S. aureus, S. epidermidis, E. faecalis, E.faecium, and S. pyogenes. Moreover, compound 3a also showed a synergistic effect with some aminoglycosides.
