113108-87-5Relevant academic research and scientific papers
Vilsmeier Reactions of 2-Alkyl-2-cyclohexen-1-ones: A Novel Route to Dihydrobenzaldehydes, the Formation of Allyl Alcohols as By-products, and the X-ray Crystallographic Structure of 3-Chloro-2-methyl-2-cyclohexen-1-ol
Katritzky, Alan R.,Wang, Zuoquan,Marson, Charles M.,Offermann, Rick J.,Koziol, Anna E.,Palenik, Gus J.
, p. 999 - 1004 (2007/10/02)
A series of 2-alkyl-2-cyclohexen-1-ones on reaction with 4-formylmorpholine in the presence of POCl3 gave the corresponding 3-alkyl-2-chloro-5,6-dihydrobenzaldehydes, usually accompanied by significant amounts of allylic alcohols as by-products.The structure of the allylic alcohol 12a from 2-methyl-2-cyclohexen-1-one was confirmed by X-ray analysis.The allylic alcohols are probably formed by addition of oxyanions to Vilsmeier intermediates.
