113133-29-2Relevant academic research and scientific papers
Enantioselective Birch Reduction and Reductive Alkylations of Chiral 2-Phenylbenzoic Acid Derivatives. Application to the Synthesis of Hydrofluoren-9-ones, Hydrophenanthren-9-ones, and (-)-(1R,2R)-2-Phenylcyclohexanamine
Schultz, Arthur G.,Macielag, Mark,Podhorez, David E.,Suhadolnik, Joseph C.
, p. 2456 - 2464 (2007/10/02)
Reductive alkylations of the chiral 2-phenylbenzoic acid amide 1 give 3-alkyl-4-phenylcyclohex-1-ene-3-carboxylic acid derivatives 2a-d with high diastereoselectivities.The chiral auxiliary can be removed by reaction with methyllithium to give enantiomeri
