113138-07-1

Upstream product

• 186581-53-3 diazomethane 
• 1820-59-3 2,2',4,4'-tetranitro-1,1'-biphenyl 
• 35387-94-1 2-iodo-1-methoxy-3-methylbenzene 
• 113165-00-7 2',2''-di-iodo-4'',6'-di-isopropoxy-4,4'''-dimethoxy-2,2'''-dimethyl-m-quaterphenyl 
• 113138-06-0 4'',6'-di-isopropoxy-4,4'''-dimethoxy-2,2'''-dimethyl-m-quaterphenyl-2',2''-diamine 
• 113138-04-8 6'-isopropoxy-4,4'''-dimethoxy-2,2'''-dimethyl-2',2'',4''-trinitro-m-quaterphenyl 
• 113137-97-6 4,4'''-dimethoxy-2,2'''-dimethyl-2',2'',4'',6'-tetranitro-m-quaterphenyl 
• 113138-01-5 4'',6'-di-isopropoxy-4,4'''-dimethoxy-2,2'''-dimethyl-2',2''-dinitro-m-quaterphenyl 
• 100-84-5 1-methoxy-3-methyl-benzene 

Relevant academic research and scientific papers

Synthesis of Substituted Dibenzophospholes. Part 8. Synthesis and Resolution of Atropisomers of a 4,6-Diaryldibenzophosphole

Regiospecific replacement of the 4''- and 6'-nitro groups in a 2,2'',4'',6'-teranitro-m-quaterphenyl by alkoxy groups has been effected in two ways: (i) the dialkali salts of α-oximinoalkanoic acids replaced one nitro group by a hydroxy group; after O-alkylation the other alkoxydenitration was effected by sodium benzaldehyde oxime followed by O-alkylation; (ii) both nitro groups were replaced by treatment with sodium 2,2-dimethoxy-1,2-diphenylethanone oximate followed by acidic hydrolysis, alkaline cleavage, and O-alkylation.From the product, synthetic procedures already developed gave 3,7-di-isopropoxy-5-methoxy-4,6-bis-(4-methoxy-2-methyl)dibenzophosphole 5-oxide, separated by chromatography into one racemic and two meso forms.The thermal interconversion of the three forms was demonstrated and measured.The racemic form was resolved by high-performance liquid chromatography (h.p.l.c.) on a chiral column.