113140-21-9

Upstream product

• 937-20-2 p-chlorophenacyl chloride 
• 82585-51-1 1-phthalimido-2-(4-chlorophenyl)-2-ethanone 
• 141-97-9 ethyl acetoacetate 
• 91857-91-9 3-(4-chloro-phenyl)-1H-pyrazol-4-ylamine 

Downstream Products

• 113140-22-0 3-(4-chloro-phenyl)-5-methyl-1H-pyrazolo[4,3-b]pyridin-7-ol 
• 113140-23-1 7-chloro-5-methyl-3-(4-chlorophenyl)-1H-pyrazolo[4,3-b]pyridine 

Relevant academic research and scientific papers

Synthesis of 3-phenylpyrazolo[4,3-b]pyridines via a convenient synthesis of 4-amino-3-arylpyrazoles and SAR of corticotropin-releasing factor receptor type-1 antagonists

3-Phenylpyrazolo[4,3-b]pyridines were synthesized via a cyclization of 4-amino-3-phenylpyrazoles 11-13 with ethyl acetoacetate. These compounds were found to be potent CRF1 antagonists. The 2-alkylpyrazolo[4,3-b]pyridines were more polar but le