1132-69-0Relevant articles and documents
Kinetics and Mechanism of the Aminolysis of Phenyl and 4-Nitrophenyl Chlorothionoformates
Castro, Enrique A.,Cubillos, Maria,Santos, Jose G.
, p. 4395 - 4397 (1997)
The reactions of a series of secondary alicyclic amines with the title substrates are subjected to a kinetic investigation in aqueous solution, 25 °C, ionic strength 0.2 M (maintained with KCl). Under amine excess pseudo-first-order rate coefficients (kobsd) are found. The plots of kobsd against concentration of free amine at constant pH are linear, with the slopes (kN) independent of pH. The Broensted-type plots obtained (log kN vs amine pKa) for the aminolysis of both substrates are linear with the same slope, β = 0.26. From this value, the kinetic law, and the analysis of products, it is deduced that these reactions proceed through a zwitterionic tetrahedral addition intermediate (T±) on the reaction path, and its formation is the rate-determining step. From a comparison of the present reactions with the concerted aminolysis of substituted phenyl chloroformates in acetonitrile it is inferred that the change of S- by O- in T± and that of water by acetonitrile as solvent destabilizes T± in such a way that the stepwise reaction becomes enforced concerted.
Preparation of alkyl and aryl chlorodifluoromethyl ethers using BrF 3
Hagooly, Youlia,Sasson, Revital,Welch, Michael J.,Rozen, Shlomo
experimental part, p. 2875 - 2880 (2009/04/07)
Both alkyl and aryl chlorothioformates could readily be obtained from the corresponding alcohols and thiophosgene. These families of compounds were treated with BrF3 to form the corresponding alkyl and aryl chlorodifluoromethyl ethers in 60-85% yields. The method is suitable for constructing a variety of aliphatic as well as electron-deficient aromatic chlorodifluoromethyl ethers. The reactions proceed under mild conditions and short reaction times. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
Episulfidation of strained cycloalkenes in the thermolysis of 5-aryloxy-1,2,3,4-thiatriazoles
Adam, Waldemar,Bargon
, p. 1959 - 1962 (2007/10/03)
The thermolysis of 5-aryloxythiatriazoles 1 in the presence of norbornene (2a) and trans-cyclooctene (trans-2b) affords the corresponding thiiranes 3a and trans-3b in moderate yields. First-order kinetics are observed, suggesting that a sulfur intermediate, presumably dinitrogen sulfide, is generated in the fragmentation process of 1, which then serves as the active sulfur atom donor.