113200-70-7Relevant academic research and scientific papers
Lanthanide- and DMSO-Induced Ring Opening of 2-Iminooxetanes: Synthesis of β-Lactams and β-Keto Amides
Barbaro, Gaetano,Battaglia, Arturo,Giorgianni, Patrizia
, p. 1020 - 1025 (2007/10/02)
2-Iminooxetanes (1), generated by lanthanide-catalyzed heterocycloaddition of aldehydes to ketene imines, are versatile synthons for β-lactams (2) and for β-keto amides (3).Conversion of 1 into 2 and 3 can be accomplished by either lanthanide-induced or o
2-IMINOXETANES FROM KETENIMINE-ALDEHYDE CYCLOADDITIONS. PART 1: SYNTHESIS AND CONTROLLED RING OPENING OF 2-N-p-TOLYLIMINO-3,3-DIMETHYL-4-PHENYLOXETANE
Barbaro, Gaetano,Battaglia, Arturo,Giorgianni, Patrizia
, p. 2995 - 2998 (2007/10/02)
Regiospecific cycloaddition of benzaldehyde to dimethylketene - N-p-tolylimine, catalyzed by lanthanide shift reagents, afforded the corresponding 2-iminoxetane.Controlled ring opening showed the oxetane to be a versatile building block for the synthesis of the corresponding acyclic -aminoalcohol, β-keto and β-hydroxyamide.In addition isomerization produced the corresponding 2-azetidinone (β-lactam).
