113200-91-2

Upstream product

• 127298-78-6 (3R,4R,5R)-1-benzyl-4-benzyloxy-3-hydroxy-5-(methoxymethoxy)methyl-2-pyrrolidinone 
• 1579996-41-0 (2R,3R,4R)-1-benzyl-3,4-bis(benzyloxy)-2-(trityloxymethyl)-pyrrolidine 
• 154815-48-2 (3S,4R,5R)-1-benzyl-4-benzyloxy-3-hydroxy-5-methoxymethoxymethyl-2-pyrrolidinone 
• 154815-47-1 (3S,4R,5R)-3-benzoyloxy-1-benzyl-4-benzyloxy-5-methoxymethoxymethyl-2-pyrrolidinone 
• 154815-46-0 (3R,4S,5S)-1-Benzyl-3,4,5-trihydroxy-5-methoxymethoxymethyl-pyrrolidin-2-one 
• 113571-55-4 (3R,4R,5R)-1-benzyl-3,4-bis(benzyloxy)-5-methoxymethoxymethyl-2-pyrrolidinone 
• 113571-53-2 (S)-1-benzyl-5-methoxymethoxymethyl-2-oxo-3-pyrroline 
• 154815-43-7 (S)-1-benzyl-5-methoxymethoxymethyl-2-pyrrolidinone 
• 94615-12-0 (S)-5-(methoxymethoxy)methyl-2-pyrrolidinone 
• 100-39-0 benzyl bromide 
• 608514-58-5 (2R,3R,4R)-1-Benzyl-3,4-bis-benzyloxy-2-vinyl-pyrrolidine 
• 357278-33-2 Benzyl-{(R)-1-[(2R,3S)-3-(tert-butyl-diphenyl-silanyloxymethyl)-oxiranyl]-allyl}-amine 
• 357278-35-4 [(2S,3R)-3-((R)-1-Benzylamino-allyl)-oxiranyl]-methanol 
• 357278-46-7 (1R,2R,5S)-3-Benzyl-2-vinyl-6-oxa-3-aza-bicyclo[3.1.0]hexane 

Downstream Products

• 100991-92-2 (2R,3R,4R)-3,4-dihydroxy-2-hydroxymethylpyrrolidine hydrochloride 
• 154815-50-6 (2S,3R,4R)-1-Benzyl-3,4-bis-benzyloxy-pyrrolidine-2-carbaldehyde 
• 100937-52-8 1,4-dideoxy-1,4-imino-D-arabitol 
• 113200-92-3 (2R,3R,4R)-N-benzyl-3,4-bis(benzyloxy)-2-<(1R)-1-hydroxy-3-butenyl>-pyrrolidine 
• 113299-94-8 (2R,3R,4R)-N-benzyl-3,4-bis(benzyloxy)-2-<(1S)-1-hydroxy-3-butenyl>-pyrrolidine 
• 113200-93-4 (2R,3R,4R)-N-benzyl-2-<(1S)-1-benzyloxy-3-butenyl>-3,4-bis(benzyloxy)pyrrolidine 
• 154815-51-7 (2R,3R,4R)-N-benzyl-2-<(1R)-1-benzyloxy-3-butenyl>-3,4-bis(benzyloxy)pyrrolidine 
• 113200-94-5 (2R,3R,4R)-N-benzyl-2-<(1S)-1-benzyloxy-4-hydroxybutyl>-3,4-bis(benzyloxy)pyrrolidine 
• 154815-52-8 (2R,3R,4R)-N-benzyl-2-<(1R)-1-benzyloxy-4-hydroxybutyl>-3,4-bis(benzyloxy)pyrrolidine 
• 191851-21-5 tert-butyl (2R,3R,4R)-3,4-bis(benzyloxy)-2-(hydroxymethyl)-pyrrolidine-1-carboxylate 
• 1567687-80-2 C₁₉H₂₃NO₃ 

Relevant academic research and scientific papers

Synthesis of pyrrolidine iminosugars, (-)-lentiginosine, (-)-swainsonine and their 8a-epimers from d-glycals

Synthesis of pyrrolidine iminosugars has been described from d-glycals via dihydroxylation, oxidative cleavage and double nucleophilic displacement as the key steps. The pyrrolidines obtained have been utilized for the synthesis of important bicyclic iminosugars, viz. (-)-lentiginosine and (-)-swainsonine and their 8a-epimers, which are known to be glycosidase inhibitors.

A flexible route towards five-membered ring imino sugars and their novel 2-deoxy-2-fluoro analogues

A flexible route towards five-membered ring imino sugars starting from a chiral α,β-epoxy aldehyde has been developed. The approach relies on the use of the versatile epoxyamine intermediate 4, from which regiocontrolled epoxide opening affords diastereos

Stereoselective synthesis of (+)-1,8-Di-epi- and (-)-1-epi-swainsonine from an (S)-pyroglutamic acid derivative

(+)-1,8-Di-epi-swainsonine (15) and (-)-1-epi-swainsonine (17) were synthesized stereoselectively from an (S)-pyroglutamic acid derivative (1a). A (2R,3R,4R)-3,4-dihydroxy-2-hydroxymethylpyrrolidine derivative (6a) was prepared by cis-dihydroxylation of a

SYNTHESES OF (-)-1-EPI-SWAINSONINE AND (+)-1,8-DI-EPI-SWAINSONINE

The syntheses of (-)-epi-swainsonine and (+)-1,8-di-epi-swainsonine have been achieved from (S)-glutamic acid.