1132093-88-9Relevant academic research and scientific papers
A Highly Reduced Ni-Li-Olefin Complex for Catalytic Kumada-Corriu Cross-Couplings
Nattmann, Lukas,Lutz, Sigrid,Ortsack, Pascal,Goddard, Richard,Cornella, Josep
supporting information, p. 13628 - 13633 (2018/10/24)
The catalytic activity of a highly reduced Ni catalyst in the context of a Kumada-Corriu cross-coupling has been studied. This nickel complex is characterized by its high electron density, stabilized by simple olefin ligands in combination with two Li ions. Landmark reactivity has been found with this precatalyst which operates at cryogenic temperatures, thus allowing the presence of sensitive functionalities. Structural elucidation of oxidative addition intermediates and their reactivity suggest highly reduced species being operative in the C-C bond forming event.
A one-pot synthesis of novel functionalized (E)-β-arylvinyl bromides from anti-2,3-dibromo-3-(4-carboxyphenyl)propanoic acid
Kuang, Chunxiang,Jiang, Yubo,Yang, Qing,Zhang, Wensheng,Wen, Yaolin
experimental part, p. 865 - 870 (2009/03/11)
A facile one-pot synthesis of functionalized (E)-β-arylvinyl bromides bearing various 4-alkoxy-carbonyl and 4-aryloxycarbonyl groups was achieved by debrominative decarboxylation of anti-2,3-dibromo-3-(4-carboxyphenyl)propanoic acid in the presence of AgOAc and subsequent esterification in the presence of dicyclohexyl carbodiimide and dimethylaminopyridine. This method gives (E)-β-arylvinyl bromides in high stereoselectivities and high yields, and tolerates aldehyde, ester, and nitro functional groups.
