1132093-90-3Relevant academic research and scientific papers
A one-pot synthesis of novel functionalized (E)-β-arylvinyl bromides from anti-2,3-dibromo-3-(4-carboxyphenyl)propanoic acid
Kuang, Chunxiang,Jiang, Yubo,Yang, Qing,Zhang, Wensheng,Wen, Yaolin
experimental part, p. 865 - 870 (2009/03/11)
A facile one-pot synthesis of functionalized (E)-β-arylvinyl bromides bearing various 4-alkoxy-carbonyl and 4-aryloxycarbonyl groups was achieved by debrominative decarboxylation of anti-2,3-dibromo-3-(4-carboxyphenyl)propanoic acid in the presence of AgOAc and subsequent esterification in the presence of dicyclohexyl carbodiimide and dimethylaminopyridine. This method gives (E)-β-arylvinyl bromides in high stereoselectivities and high yields, and tolerates aldehyde, ester, and nitro functional groups.
