113248-64-9

Basic information

• Product Name: (4-FLUORO-BENZYL)-PYRIDIN-3-YLMETHYL-AMINE
• Synonyms: N-(4-FLUOROBENZYL)-N-(3-PYRIDINYLMETHYL)AMINE;(4-FLUORO-BENZYL)-PYRIDIN-3-YLMETHYL-AMINE;N-(4-fluorobenzyl)-1-(pyridin-3-yl)methanamine
• CAS NO: 113248-64-9
• Molecular Formula: C13H13FN2
• Molecular Weight: 216.25
• Mol File: 113248-64-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 333.6 °C at 760 mmHg
• Flash Point: 155.6 °C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.000135mmHg at 25°C
• PKA: 7.58±0.20(Predicted)
• CAS DataBase Reference: (4-FLUORO-BENZYL)-PYRIDIN-3-YLMETHYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-FLUORO-BENZYL)-PYRIDIN-3-YLMETHYL-AMINE(113248-64-9)
• EPA Substance Registry System: (4-FLUORO-BENZYL)-PYRIDIN-3-YLMETHYL-AMINE(113248-64-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 113248-64-9(Hazardous Substances Data)

Usage

General Description

(4-FLUORO-BENZYL)-PYRIDIN-3-YLMETHYL-AMINE is a chemical compound with the molecular formula C13H13FN2. It is a derivative of benzylpyridine, containing a fluorine atom on the benzyl group and a pyridin-3-ylmethylamine moiety. (4-FLUORO-BENZYL)-PYRIDIN-3-YLMETHYL-AMINE is commonly used in pharmaceutical research and development, particularly in the synthesis of potential drug candidates. Its specific properties and potential uses in medicine would depend on its pharmacological and toxicological profiles, which are subject to further investigation and testing.

InChI:InChI=1/C13H13FN2/c14-13-5-3-11(4-6-13)8-16-10-12-2-1-7-15-9-12/h1-7,9,16H,8,10H2/p+1

Upstream product

• 3731-52-0 3-Aminomethylpyridine 
• 459-57-4 4-fluorobenzaldehyde 
• 500-22-1 3-pyridinecarboxaldehyde 
• 140-75-0 para-fluorobenzylamine 
• 745814-24-8 C₁₃H₁₁FN₂ 

Relevant articles and documents

4-(N,N-diarylmethylamine)furan-2(5H)-one derivatives, and preparation method and application thereof

The invention discloses 4-(N,N-diarylmethylamine)furan-2(5H)-one derivatives, and a preparation method and application thereof. The derivatives are as shown in a general formula (I) which is describedin the specification. In the formula (I), R1 is 6-chloropyridin-3-yl, pyridin-3-yl, 6-fluoropyridin-3-yl, 6-bromopyridin-3-yl or 6-trifluoromethylpyridin-3-yl; R2 is 4-chloro-3-fluorobenzyl, thienyl,2,4,5-trifluorobenzyl, 4-trifluoromethylbenzyl, 2,6-difluorobenzyl, 4-bromobenzyl, 2-chloro-6-fluorobenzyl, 2-fluorobenzyl, 3,4-difluorobenzyl, 3-chloro-4-fluorobenzyl, 3,4,5-trifluorobenzyl, 2,4,6-trifluoro Benzyl, 4-fluoro-2-methylbenzyl, 3-bromo-4-fluorobenzyl, 2-fluorobenzonitrile, 4-fluoro-3-methylbenzyl, 3,4-dichlorobenzyl, 2-chlorobenzyl, 2,4,5-trifluorobenzyl, 4-fluorobenzyl, 3-bromobenzyl, 3-chlorobenzyl, 2,3,4,5,6-pentafluorobenzyl, 4-fluoro-3-nitrobenzyl, 5-chloro-2-fluorobenzyl, cyanobenzyl, 3-nitrobenzyl or 4-((3,3-dichloroallyl)oxy)benzyl. The derivatives provided by the invention have good activity on aphids attacking broad beans; preparation process is simple; and production cost is low.

Flow synthesis of organic azides and the multistep synthesis of imines and amines using a new monolithic triphenylphosphine reagent

Here we describe general flow processes for the synthesis of alkyl and aryl azides, and the development of a new monolithic triphenylphosphine reagent, which provides a convenient format for the use of this versatile reagent in flow. The utility of these new tools was demonstrated by their application to a flow Staudinger aza-Wittig reaction sequence. Finally, a multistep aza-Wittig, reduction and purification flow process was designed, allowing access to amine products in an automated fashion.