113250-99-0

Basic information

• Product Name: 2-Furancarboxaldehyde, 5-(1,4-dihydro-1,4-dioxo-2-naphthalenyl)-, 2-(2,2-dimethylhydrazone)
• Synonyms: 2-Furancarboxaldehyde, 5-(1,4-dihydro-1,4-dioxo-2-naphthalenyl)-, 2-(2,2-dimethylhydrazone)
• CAS NO: 113250-99-0
• Molecular Formula: C17H14N2O3
• Molecular Weight: 294.30466
• Mol File: 113250-99-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Furancarboxaldehyde, 5-(1,4-dihydro-1,4-dioxo-2-naphthalenyl)-, 2-(2,2-dimethylhydrazone)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Furancarboxaldehyde, 5-(1,4-dihydro-1,4-dioxo-2-naphthalenyl)-, 2-(2,2-dimethylhydrazone)(113250-99-0)
• EPA Substance Registry System: 2-Furancarboxaldehyde, 5-(1,4-dihydro-1,4-dioxo-2-naphthalenyl)-, 2-(2,2-dimethylhydrazone)(113250-99-0)

Safety Data

• Hazardous Substances Data: 113250-99-0(Hazardous Substances Data)

Upstream product

• 14064-21-2 2-furaldehyde dimethylhydrazone 
• 130-15-4 [1,4]naphthoquinone 

Relevant articles and documents

Studies on quinones. Part 42: Synthesis of furylquinone and hydroquinones with antiproliferative activity against human tumor cell lines

The preparation of furyl-1,4-quinone and hydroquinones by reaction of 2-furaldehyde N,N-dimethylhydrazone with benzo- and naphthoquinones is reported. Access to furylnaphthoquinones from unactivated quinones requires acid-induced conditions, however oxidative coupling reactions of activated quinones proceed under neutral conditions. The in vitro cytotoxic activity of the prepared compounds against a panel of three human cancer cell lines has been studied. Most of the furyl-1,4-quinones exhibited good antiproliferative activity (GI50 = 6.5-33.5 μm) against the MCF-7, NCI-H460, and SF-268 (CNS cancer) cell lines chosen for testing.