1132667-71-0

Basic information

• Product Name: diethyl 3-(2-chlorophenyl)-1-tosylaziridine-2,2-dicarboxylate
• Synonyms: diethyl 3-(2-chlorophenyl)-1-tosylaziridine-2,2-dicarboxylate
• CAS NO: 1132667-71-0
• Molecular Weight: 451.928
• Mol File: 1132667-71-0.mol

Chemical Properties

• CAS DataBase Reference: diethyl 3-(2-chlorophenyl)-1-tosylaziridine-2,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 3-(2-chlorophenyl)-1-tosylaziridine-2,2-dicarboxylate(1132667-71-0)
• EPA Substance Registry System: diethyl 3-(2-chlorophenyl)-1-tosylaziridine-2,2-dicarboxylate(1132667-71-0)

Safety Data

• Hazardous Substances Data: 1132667-71-0(Hazardous Substances Data)

Upstream product

• 135822-90-1 o-chloro-N-tosylbenzaldimine 
• 105-53-3 diethyl malonate 

Relevant articles and documents

Facile iodine(III)-induced oxidative cycloaddition of N-sulfonyl imines with methylene compounds under neutral conditions

An efficient oxidative cycloaddition of N-sulfonyl imines with methylene compounds using PhIO with a catalytic amount of KI under neutral conditions, which affords 2,2-difunctionalized aziridines in good to excellent yields, is reported.

Iodobenzene diacetate/tetrabutylammonium iodide-induced aziridination of N-tosylimines with activated methylene compounds under mild conditions

Aziridination of N-tosylimines with activated methylene compounds induced by iodobenzene diacetate [PhI(OAc)2] and tetrabutylammonium bromide [Bu4NBr] afforded the corresponding 2,2-difunctionalized aziridines in good yields with the aid of a catalytic amount of base. The reaction is hypothesized to proceed via a tandem nucleophilic addition-oxidative cyclization pathway.