113274-21-8

Basic information

• Product Name: (2-Azidoethoxy)(tert-butyl)diMethylsilane
• Synonyms: (2-Azidoethoxy)(tert-butyl)diMethylsilane
• CAS NO: 113274-21-8
• Molecular Formula: C₈H₁₉N₃OSi
• Molecular Weight: 201.34146
• Mol File: 113274-21-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-Azidoethoxy)(tert-butyl)diMethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Azidoethoxy)(tert-butyl)diMethylsilane(113274-21-8)
• EPA Substance Registry System: (2-Azidoethoxy)(tert-butyl)diMethylsilane(113274-21-8)

Safety Data

• Hazardous Substances Data: 113274-21-8(Hazardous Substances Data)

Usage

General Description

(2-Azidoethoxy)(tert-butyl)diMethylsilane is a chemical compound with the formula (CH3)2MeSiC(CH3)3O(CH2)2N3. It is a versatile reagent widely used in organic synthesis, particularly in the preparation of polymers, silicon-containing compounds, and materials with potential pharmaceutical applications. It is a colorless liquid that is highly reactive due to the presence of the azide group, making it useful for the functionalization of organic compounds and the introduction of silicon-based functionality. Due to its potential explosive nature, it should be handled with caution and stored and used in accordance with safety guidelines.

Upstream product

• 288-32-4 1H-imidazole 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1517-05-1 2-azidoethanol 

Downstream Products

• 1204508-63-3 methyl (5S,6R)-6-(2-azidoethoxy)-6-(2,3-dimethoxyphenyl)-5-methylhex-3-ynoate 
• 1204508-71-3 methyl (5S,6S)-6-(2-azidoethoxy)-6-cyclohexyl-5-methylhex-3-ynoate 
• 1204508-61-1 methyl (5S,6R)-6-(2-azidoethoxy)-5-methyl-6-(2-nitrophenyl)hex-3-ynoate 
• 1204508-56-4 methyl (5S,6R)-6-(2-azidoethoxy)-6-(2-bromophenyl)-5-methylhex-3-ynoate 
• 1204508-54-2 methyl (5S,6R)-6-(2-azidoethoxy)-5-methyl-6-phenylhex-3-ynoate 
• 1204508-59-7 methyl (5S,6R)-6-(2-azidoethoxy)-6-(4-chlorophenyl)-5-methylhex-3-ynoate 
• 1204508-65-5 methyl (5S,6R)-6-(2-azidoethoxy)-5-methyl-6-p-tolylhex-3-ynoate 
• 1204508-69-9 methyl (5S,6S)-6-(2-azidoethoxy)-5-methyl-8-phenyloct-3-ynoate 
• 215050-00-3 4-(2-azido-ethoxy)-3-nitro-benzoic acid methyl ester 

Relevant articles and documents

Substituted 1-(2-chloroethyl)-3-acyl-3-alkyltriazenes

A substituted 1-(2-chloroethyl)-3-acyl-3-alkyltriazene of the formula: STR1 in which R1 is 1-oxoalkyl containing from two to eight carbon atoms, fluorinated 1-oxoalkyls containing from two to eight carbon atoms and substituted with up to three fluorine atoms, benzoyl, phenylacetyl, carboalkoxy containing from two to eight carbon atoms, fluorinated carboalkyl containing from two to eight carbon atoms and up to three fluorine atoms, carbophenoxy, N-phenyl aminocarbonyl, N-alkyl aminocarbonyl containing from two to eight carbon atoms, thiocarbamoyl, N-alkylthiocarbamoyls with from two to eight carbon atoms, N-phenylthiocarbamoyl, dialkylphosphonates in which the alkyl groups can be the same or different and each contains from one to seven carbon atoms, phenylsulfonyl, and meta or para-substituted phenylsulfonyl in which the meta or para substituent is methyl, ethyl, methoxy, ethoxy, fluoro and chloro; and R2 is indepedently alkyl containing from one to seven carbon atoms, fluoroalkyl containing from two to seven carbon atoms and from one to three fluorine atoms in which the α carbon of the fluoroalkyl group is not substituted with fluorine, benzyl, meta or para-substituted benzyl in which the meta or para substituent is chloro, fluoro, and alkoxy with from one to three carbon atoms, alkenyl containing from two to seven carbon atoms, and alkynyl containing from two to seven carbon atoms, useful as antitumor agents.