1132941-66-2

Basic information

• Product Name: 4-((tert-butoxycarbonyl)amino)phenyl methanesulfonate
• Synonyms: 4-((tert-butoxycarbonyl)amino)phenyl methanesulfonate
• CAS NO: 1132941-66-2
• Molecular Weight: 287.337
• Mol File: 1132941-66-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-((tert-butoxycarbonyl)amino)phenyl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((tert-butoxycarbonyl)amino)phenyl methanesulfonate(1132941-66-2)
• EPA Substance Registry System: 4-((tert-butoxycarbonyl)amino)phenyl methanesulfonate(1132941-66-2)

Safety Data

• Hazardous Substances Data: 1132941-66-2(Hazardous Substances Data)

Upstream product

• 54840-15-2 4-N-tert-butoxycarbonylaminophenol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1132941-68-4 4-aminophenyl methanesulfonate hydrochloride 
• 143090-18-0 tert-butyl N-(4-cyanophenyl)carbamate 

Relevant articles and documents

Cyanation of unactivated aryl chlorides and aryl mesylates catalyzed by palladium and hemilabile MOP-type ligands

Palladium-catalyzed cyanation of aryl halides and pseudo halides with potassium hexacyanoferrate is described employing the hemilabile, bulky, and electron-rich MOP-type ligands. When the mixture of t-BuOH and H2O was used as the solvent and K2CO3 as the base, the MOP-type ligands showed high efficiency for the palladium-catalyzed cyanation. The effect of ligand structure was studied in detail, and 2-di-tert-butylphosphino-2′-isopropoxy-1,1′-binaphthyl was the more effective for the cyanation. The catalyst system allows the cyanation of unactivated aryl chlorides, and even aryl mesylates to occur in good yields. Furthermore, the reactivity of different arylated reagents in the catalytic system was found to be: ArBr > ArCl >> ArOMs > ArOSO2Im > ArOSO2NMe2.