113330-85-1Relevant academic research and scientific papers
SYNTHESIS OF 5-ALKYL-3H-THIOLEN-2-ONES AND 5-ALKYL-3H-FURAN-2-ONES AND CONDENSATION REACTIONS AT THE HETEROCYCLIC METHYLENE GROUP
Sedavkina, V. A.,Morozova, N. A.,Egorova, A. Yu.,Ostroumov, I. G.
, p. 377 - 380 (2007/10/02)
The intramolecular cyclization of γ-ketocarboxylic acids and their esters gives 5-alkylsubstituted 3H-thiolen-2-ones and 3H-furan-2-ones.It was shown that reaction occured at the heterocyclic methylene group and that the conditions under which the reaction took place depended on the nature of the heterocyclic atom.
