14369-94-9

Basic information

• Product Name: 4-Oxoheptanoic acid ethyl ester
• Synonyms: 4-Ketoenanthic acid ethyl ester;4-Oxoheptanoic acid ethyl ester
• CAS NO: 14369-94-9
• Molecular Formula: C₉H₁₆O₃
• Molecular Weight: 172.23
• Mol File: 14369-94-9.mol

Chemical Properties

• Boiling Point: 240.3°C at 760 mmHg
• Flash Point: 98°C
• Appearance: /
• Density: 0.969g/cm³
• Vapor Pressure: 0.0382mmHg at 25°C
• Refractive Index: 1.426
• CAS DataBase Reference: 4-Oxoheptanoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Oxoheptanoic acid ethyl ester(14369-94-9)
• EPA Substance Registry System: 4-Oxoheptanoic acid ethyl ester(14369-94-9)

Safety Data

• Hazardous Substances Data: 14369-94-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H16O3/c1-3-5-8(10)6-7-9(11)12-4-2/h3-7H2,1-2H3

Upstream product

• 2459-05-4 malonic acid monoethyl ester 
• 123-72-8 butyraldehyde 
• 64-17-5 ethanol 
• 41658-17-7 1-bromo-hept-1-yn-4-one 
• 140-88-5 ethyl acrylate 
• 110-62-3 pentanal 
• 29901-85-7 (E)-hept-3-enoic acid 
• 54340-71-5 (E)-ethyl hept-3-enoate 
• 111-92-2 dibutylamine 
• 41117-77-5 2-butyrylsuccinic acid diethyl ester 
• 10031-90-0 ethyl 3-(furan-2-yl)propanoate 
• 4208-61-1 ethylfurfuryl alcohol 

Downstream Products

• 1253517-81-5 C₃₄H₂₉N₅O 
• 1253517-80-4 C₂₉H₂₅ClN₄O 
• 1253517-79-1 C₂₉H₂₅ClN₄O 
• 1253517-78-0 C₂₈H₂₃ClN₄O 
• 1253517-77-9 C₂₉H₂₅ClN₄O 
• 1253517-76-8 C₂₉H₂₅ClN₄O₂ 
• 1253517-89-3 C₂₈H₂₂ClN₃O₃ 
• 1253517-88-2 C₂₉H₂₅N₃O₃ 
• 1253517-87-1 C₂₉H₂₅N₃O₃ 
• 1253517-86-0 C₂₈H₂₃N₃O₃ 
• 1253517-85-9 C₃₄H₂₆Cl₂FN₅O 
• 1253517-84-8 C₃₄H₂₇ClFN₅O 
• 1253517-83-7 C₃₅H₃₁N₅O 
• 1253517-82-6 C₃₄H₂₈ClN₅O 

Relevant articles and documents

Photoredox-Catalyzed α-C(sp3)-H Activation of Unprotected Secondary Amines: Facile Access to 1,4-Dicarbonyl Compounds

A photoredox-catalyzed α-C(sp3)-H activation approach of unprotected secondary amines is reported. Such transformations provide facile access to various 1,4-dicarbonyl compounds using readily available amines and α,β-unsaturated compounds as feedstocks under air conditions. The substrate scope of this method is broad, and a wide array of functional groups are tolerated.

Regioselective ring opening and isomerization reactions of 3,4-epoxyesters catalyzed by boron trifluoride

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A series of polyether-substituted triazolium ionic liquids catalysts have been first synthesized for resolving the problem of separation and reuse of Stetter catalysts. The catalysts possess the properties of critical solution temperature (CST) and inverse temperature-dependent solubility in toluene/heptane solvents. Based on these properties, the catalysts can achieve the catalytic process named as thermoregulated phase-separable catalysis (TPSC) with the characteristic of homogeneous reaction at higher temperature and phase-separation at lower temperature. The novel TPSC system has been successfully applied for Stetter reaction of furfural or butanal with ethyl acrylate. The experimental results have showed that the novel catalysts exhibit excellent TPSC with high recycling efficiency.

Polyether-substituted thiazolium ionic liquid catalysts - A thermoregulated phase-separable catalysis system for the Stetter reaction

A series of polyether-substituted thiazolium ionic liquids have been synthesized and used as catalysts in the Stetter reaction. The ionic liquids are a thermoregulated phase-separable catalysis (TPSC) system, because they possess the properties of critical solution temperature (CST) and inverse temperature-dependent solubility in toluene-heptane. The results showed that the novel TPSC system exhibits high recycling efficiency, and provides a potential route for a environmentally benign Stetter reaction. The Royal Society of Chemistry 2010.

Radical alkylation of bis(silyloxy)enamine derivatives of organic nitro compounds

(Chemical Equation Presented) Alkylation β to a nitro group by radical chemistry is made possible by initial conversion of the organic nitro compound into a bis(silyloxy)enamine (see scheme; TBSOTf=tert-butyldimethylsilyl trifluoromethanesulfonate). An advantage of the method is the simultaneous conversion of the nitro group into a synthetically useful oxime ether group.

Pyridazine derivatives useful as components of liquid crystal mixtures

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Thiazolium salt catalysed addition of aliphatic aldehydes to α,β-unsaturated esters and nitriles leads to γ-ketocarboxylic esters (1-24) and γ-ketonitriles (25-32).