1133388-22-3Relevant academic research and scientific papers
Stereocontrolled solid-phase synthesis of oligonucleoside H-phosphonates by an oxazaphospholidine approach
Iwamoto, Naoki,Oka, Natsuhisa,Sato, Terutoshi,Wada, Takeshi
supporting information; experimental part, p. 496 - 499 (2009/04/14)
(Chemical Equation Presented) Stereodefined oligonucleoside H-phosphonates were synthesized on a solid support using diastereopure nucleoside 3′-O-oxazaphospholidine monomers. Several stereodefined backbone-modified analogues were obtained with the oligonucleoside H-phosphonates as precursors (see scheme; BPRO = protected nucleobase, DMTr = 4,4′- dimethoxytrityl, Th = thymin-1-yl, TfO- = triflate).
