113352-68-4

Basic information

• Product Name: 1H-Indole-1-carboxylic acid, 6-methoxy-2-methyl-3-[[[2-(phenylthio)ethyl]imino]methyl]-, methyl ester, (E)-
• CAS NO: 113352-68-4
• Molecular Formula: C21H22N2O3S
• Molecular Weight: 382.483
• Mol File: 113352-68-4.mol

Chemical Properties

• CAS DataBase Reference: 1H-Indole-1-carboxylic acid, 6-methoxy-2-methyl-3-[[[2-(phenylthio)ethyl]imino]methyl]-, methyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-1-carboxylic acid, 6-methoxy-2-methyl-3-[[[2-(phenylthio)ethyl]imino]methyl]-, methyl ester, (E)-(113352-68-4)
• EPA Substance Registry System: 1H-Indole-1-carboxylic acid, 6-methoxy-2-methyl-3-[[[2-(phenylthio)ethyl]imino]methyl]-, methyl ester, (E)-(113352-68-4)

Safety Data

• Hazardous Substances Data: 113352-68-4(Hazardous Substances Data)

Upstream product

• 96-96-8 4-methoxy-2-nitroaniline 
• 113352-66-2 1-(4-methoxy-2-nitrophenyl)propan-2-one 
• 4147-43-7 6-methoxy-2-methylindole-3-carboxaldehyde 
• 1968-13-4 2-methyl-6-methoxy-1H-indole 
• 2014-75-7 2-(phenylthio)ethanamine 
• 113352-67-3 1-carbomethoxy-6-methoxy-3-formyl-2-methylindole 

Downstream Products

• 113352-70-8 C₃₁H₃₂N₂O₅S 
• 113352-71-9 C₃₁H₃₀N₂O₄S 
• 113689-23-9 C₃₁H₃₀N₂O₄S 
• 113774-79-1 (3aR,10bS,11S,12bS)-8-Methoxy-1-oxo-11-phenylsulfanyl-3a,11,12,12b-tetrahydro-1H,4H-6,12a-diaza-indeno[7,1-cd]fluorene-6-carboxylic acid methyl ester 
• 113352-98-0 C₃₃H₃₆N₂O₅S 
• 113352-98-0 C₃₃H₃₆N₂O₅S 
• 113352-99-1 C₃₃H₃₄N₂O₄S 
• 113352-99-1 C₃₃H₃₄N₂O₄S 
• 113352-99-1 C₃₃H₃₄N₂O₄S 
• 113352-76-4 (3aR,10bS,11R,12bS)-3a-Ethyl-8-methoxy-1-oxo-11-phenylsulfanyl-3a,11,12,12b-tetrahydro-1H,4H-6,12a-diaza-indeno[7,1-cd]fluorene-6-carboxylic acid methyl ester 
• 113378-64-6 2,3,6,7-tetradehydro-1-carbomethoxy-11β-(phenylthio)-16-methoxyaspidospermidin-8-one 
• 113352-76-4 (3aS,10bR,12bR)-3a-Ethyl-8-methoxy-1-oxo-11-phenylsulfanyl-3a,11,12,12b-tetrahydro-1H,4H-6,12a-diaza-indeno[7,1-cd]fluorene-6-carboxylic acid methyl ester 
• 113352-70-8 C₃₁H₃₂N₂O₅S 
• 113352-71-9 C₃₁H₃₀N₂O₄S 

Relevant articles and documents

METHODS FOR INDOLE ALKALOID SYNTHESIS. COMPATIBILITY OF THE 16-METHOXY SUBSTITUENT WITH THE INDOLE-2,3-QUINODIMETHANE STRATEGY TO ASPIDOSPERMA-TYPE INDOLE ALKALOIDS

The imin 8, on treatment with 10 gave 11, from which the derived sulfoxide 12 underwent intramolecular Pummerer cyclization to give 14.

Methods for Indole Alkaloid Synthesis: A Study of the Compatibility of the Indole-2,3-Quinodimethane Strategy for the Synthesis of 16-Methoxy-Substituted Aspidosperma-Type Alkaloids. Synthesis of (+)- and (-)-16-Methoxytabersonine

4-Methoxy-2-nitroaniline (5) is converted into 1-carbomethoxy-6-methoxy-3-formyl-2-methylindole (10) in an overall yield of 28percent through five steps.The derived imine from 10 and 2-(phenylthio)ethylamine on treatment with acid chloride (+/-)-12 gave h