113373-58-3Relevant academic research and scientific papers
HETERO-COPE REARRANGEMENTS - VI; SHORT AND STEREOSELECTIVE SYNTHESIS OF 2-VINYLINDOLES BY A TANDEM-PROCESS
Wilkens, Jochen,Kuehling, Andrea,Blechert, Siegfried
, p. 3237 - 3246 (2007/10/02)
The initially formed N-phenylnitrone-intermediates are converted by a tandem-reaction (cycloaddition, Cope rearrangement, retro-Michael addition, and indolization) to 2-vinylindoles 7.Thus these indoles can be synthesized simply and stereoselectively in a one-pot reaction from N-phenylhydroxylamine 4, aldehydes 5, and electrondeficient allenes 6.
