113379-89-8

Basic information

• Product Name: 1H-Pyrrole-2,3-dicarboxylic acid, 1-methyl-5-phenyl-, diethyl ester
• CAS NO: 113379-89-8
• Molecular Formula: C17H19NO4
• Molecular Weight: 301.342
• Mol File: 113379-89-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-2,3-dicarboxylic acid, 1-methyl-5-phenyl-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-2,3-dicarboxylic acid, 1-methyl-5-phenyl-, diethyl ester(113379-89-8)
• EPA Substance Registry System: 1H-Pyrrole-2,3-dicarboxylic acid, 1-methyl-5-phenyl-, diethyl ester(113379-89-8)

Safety Data

• Hazardous Substances Data: 113379-89-8(Hazardous Substances Data)

Upstream product

• 623-47-2 propynoic acid ethyl ester 

Relevant articles and documents

Nucleophilic Addition to Oxazolium Salts: Stabilized Azomethine Ylides via 2-Substituted 4-Oxazolines

Treatment of oxazolium salts with cyanide generates 4-oxazolines 2 in situ.Ring opening to azomethine ylides 3 occurs spontaneously and 2 + 3 cycloadducts are obtained in the presence of acrylate, propiolate, or acetylenedicarboxylate dipolarophiles.In the case of acetylenic dipolarophiles, loss of HCN occurs under the reaction conditions and leads directly to pyrroles 5.The propiolate experiments are complicated by the formation of six-membered adducts 17 in some cases.This reaction pathway is explained by the addition of the acetylide anion derived from propiolate to the dipole, followed by cyclization.Sulfide nucleophiles can also be used to generate 4-oxazolines, but the yields of cycloadducts are lower.