113386-05-3Relevant articles and documents
New N-(benzhydryloxyalkyl)-4-(carboxy/carbamoylmethyl) piperidine derivatives with antidepressant activity
Ahmad, Y. El,Maillet,Laurent,Talab,Teste,Cedat,Fiez-Vandal,Dokhan,Ollivier
, p. 205 - 218 (2007/10/03)
Several benzhydryloxylalkylpiperidine derivatives were prepared with the aim of obtaining new antidepressant compounds. The influence of the length of the aliphatic chain and of aromatic and piperidine ring substitutions was studied. The pharmacological a
A STEREOSELECTIVE SYNTHESIS OF CIS-4-ACETONYL-1-BENZYL-3-ETHYLPIPERIDINE
Bonjoch, Josep,Linares, Ana,Guardia, Manel,Bosch, Joan
, p. 2165 - 2174 (2007/10/02)
The title compound cis-1, a potential synthon for indole alkaloid synthesis, is prepared for the first time. The synthesis starts with the condensation of 3-ethyl-4-piperidone 2 with triethyl phosphonoacetate followed by stereoselective hydrogenation of t