40748-71-8

Usage

Uses

Used in Pharmaceutical Industry:
1-Benzyl-3-ethyl-piperidin-4-one is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into the molecular structures of different drugs. Its versatility in chemical reactions allows for the creation of a wide range of medicinal compounds.
Used in Research Chemicals:
In the field of research chemistry, 1-Benzyl-3-ethyl-piperidin-4-one serves as a key component in the development of new chemical entities. Its unique structure and reactivity make it an essential building block for the synthesis of novel organic compounds with potential applications in various scientific and industrial areas.
Used in Drug Development:
1-Benzyl-3-ethyl-piperidin-4-one is utilized in drug development as a valuable tool for creating new pharmaceutical agents. Its chemical properties enable the design and synthesis of innovative drugs with improved therapeutic effects and reduced side effects.
Used in Chemical Industry:
In the chemical industry, 1-Benzyl-3-ethyl-piperidin-4-one is employed as a versatile building block for the synthesis of various organic compounds. Its unique structure and reactivity contribute to the development of new materials and products with diverse applications.

Upstream product

• 41276-30-6 C₉H₁₄O₃NC₆H₅ 
• 75-03-6 ethyl iodide 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 1334292-35-1 1-benzyl-4-(2,2-dimethylhydrazono)piperidine 
• 1237526-31-6 methyl 1-benzyl-3-ethyl-4-oxopiperidine-3-carboxylate 
• 324769-01-9 3-ethylpiperidin-3-one hydrochloride 
• 100-39-0 benzyl bromide 
• 104777-74-4 3-Ethylpiperidin-4-one 
• 57611-47-9 1-benzyl-4-oxo-piperidine-3-carboxylic acid methyl ester 
• 113385-99-2 ethyl 1-benzyl-3-ethyl-4-oxo-3-piperidinecarboxylate 

Downstream Products

• 113386-05-3 ethyl 1-benzyl-3-ethyl-1,2,5,6-tetrahydro-4-pyridineacetate 
• 113386-01-9 ethyl 1-benzyl-3-ethylpiperidine-Δ^4,α-acetate 
• 113386-00-8 ethyl 1-benzyl-3-ethylpiperidine-Δ^4,α-acetate 
• 142742-60-7 1-benzyl-3-ethyl-1-methyl-4-oxopiperidin-1-ium iodide salt 
• 1610034-12-2 1-(5-ethoxy-2-fluorophenyl)-3-ethylpiperidin-4-one 
• 325487-15-8 C₂₅H₂₆FNO₅ 
• 325487-14-7 1-benzyl-3-ethyl-4-hydroxy-4-(6-fluorobenzofuran-7-yl)piperidine 
• 113386-03-1 4-acetonyl-1-benzyl-3-ethyl-1,2,5,6-tetrahydropyridine 
• 113386-02-0 1-[1-Benzyl-3-ethyl-piperidin-(4Z)-ylidene]-propan-2-one 
• 113386-04-2 1-(1-Benzyl-3-ethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-propan-2-one 
• 113386-10-0 cis-4-Acetonyl-1-benzyl-3-ethylpiperidine 
• 113386-10-0 trans-4-acetonyl-1-benzyl-3-ethylpiperidine 

Relevant academic research and scientific papers

DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS

The invention provides dihydroisoquinoline-2(1H)-carboxamide and related compounds, pharmaceutical compositions, and their use in the treatment of medical conditions, such as cancer, and in inhibiting HPK1 activity.

Dihydropyrazole GPR40 modulators

The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.

PYRROLIDINE GPR40 MODULATORS

The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.

3,4′-Linked bis(piperidines) related to the haliclonacyclamine class of marine alkaloids: Synthesis using crossed-aldol chemistry and preliminary biological evaluations

Compounds 2-5, incorporating various elements of the 3,4′- bis(piperidine) core associated with the sponge-derived alkaloid haliclonacyclamine A (HA, 1), have been prepared through, inter alia, aldol-type reactions of N-substituted piperidin-4-ones and certain derivatives. Screening of these compounds in various assays, including an ecological one, reveals that compound 5 exhibits allelochemical properties similar to those associated with HA itself.

2′ Biaryl amides as novel and subtype selective M1 agonists. Part II: Further optimization and profiling

Further optimization of the biaryl amide series via extensively exploring structure-activity relationships resulted in potent and subtype selective M 1 agonists exemplified by compounds 9a and 9j with good rat PK properties including CNS penetration. Synthesis, structure-activity relationships, subtype selectivity for M1 over M2-5, and DMPK properties of these novel compounds are described.

SEROTONERGIC BENZOTHIOPHENES

The present invention provides serotonergic benzothiophenes of Formula (I), where A, R, R, R, R, and R are as described in the specification.

CCR8 INHIBITORS

Disclosed is an inhibitor of CCR8 that is represented by Structural Formula (I). Also disclosed are pharmaceutical compositions comprising a pharmaceutically acceptable carrier or diluent and a CCR8 inhibitor represented by Structural Formula (I). Also disclosed is a method of treating inflammatory disorders in a subject by administering a CCR8 inhibitor to the subject.

CCR8 INHIBITORS

Disclosed are CCR8 inhibitors represented by Structural Formulas (I). The variables in Structural Formula (I) are described herein. Also disclosed are methods of treating a subject with a CCR8 mediated condition, especially asthma, by administering one of the disclosed CCR8 inhibitors to the subject.

SEROTONERGIC BENZOFURANS

The present invention provides serotonergic benzofurans of Formula (I): where A, R, R, R, R, and R are as described in the specification.

A STEREOSELECTIVE SYNTHESIS OF CIS-4-ACETONYL-1-BENZYL-3-ETHYLPIPERIDINE

The title compound cis-1, a potential synthon for indole alkaloid synthesis, is prepared for the first time. The synthesis starts with the condensation of 3-ethyl-4-piperidone 2 with triethyl phosphonoacetate followed by stereoselective hydrogenation of t