40748-71-8

Basic information

• Product Name: 1-Benzyl-3-ethyl-piperidin-4-one
• Synonyms: 1-Benzyl-3-ethyl-piperidin-4-one
• CAS NO: 40748-71-8
• Molecular Formula: C₁₄H₁₉NO
• Molecular Weight: 217.30676
• Mol File: 40748-71-8.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Benzyl-3-ethyl-piperidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-3-ethyl-piperidin-4-one(40748-71-8)
• EPA Substance Registry System: 1-Benzyl-3-ethyl-piperidin-4-one(40748-71-8)

Safety Data

• Hazardous Substances Data: 40748-71-8(Hazardous Substances Data)

Usage

General Description

1-Benzyl-3-ethyl-piperidin-4-one is a chemical compound with the chemical formula C16H23NO. It is a piperidinone derivative that is commonly used as an intermediate in the synthesis of pharmaceuticals and research chemicals. 1-Benzyl-3-ethyl-piperidin-4-one is also known for its potential psychoactive effects, leading to its illegal use as a recreational drug. Its structure consists of a benzyl group, an ethyl group, and a piperidin-4-one ring, making it a versatile building block for the synthesis of various organic compounds. The chemical properties of 1-Benzyl-3-ethyl-piperidin-4-one make it a valuable tool in the development of new drugs and materials with potential applications in the pharmaceutical and chemical industries.

Upstream product

• 113385-99-2 ethyl 1-benzyl-3-ethyl-4-oxo-3-piperidinecarboxylate 
• 104777-74-4 3-Ethylpiperidin-4-one 
• 100-39-0 benzyl bromide 
• 41276-30-6 C₉H₁₄O₃NC₆H₅ 
• 1334292-35-1 1-benzyl-4-(2,2-dimethylhydrazono)piperidine 
• 75-03-6 ethyl iodide 
• 1237526-31-6 methyl 1-benzyl-3-ethyl-4-oxopiperidine-3-carboxylate 
• 324769-01-9 3-ethylpiperidin-3-one hydrochloride 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 57611-47-9 1-benzyl-4-oxo-piperidine-3-carboxylic acid methyl ester 

Downstream Products

• 325487-14-7 1-benzyl-3-ethyl-4-hydroxy-4-(6-fluorobenzofuran-7-yl)piperidine 
• 325487-15-8 C₂₅H₂₆FNO₅ 
• 1610034-12-2 1-(5-ethoxy-2-fluorophenyl)-3-ethylpiperidin-4-one 
• 113386-05-3 ethyl 1-benzyl-3-ethyl-1,2,5,6-tetrahydro-4-pyridineacetate 
• 113386-01-9 ethyl 1-benzyl-3-ethylpiperidine-Δ^4,α-acetate 
• 113386-00-8 ethyl 1-benzyl-3-ethylpiperidine-Δ^4,α-acetate 
• 142742-60-7 1-benzyl-3-ethyl-1-methyl-4-oxopiperidin-1-ium iodide salt 
• 113386-03-1 4-acetonyl-1-benzyl-3-ethyl-1,2,5,6-tetrahydropyridine 
• 113386-02-0 1-[1-Benzyl-3-ethyl-piperidin-(4Z)-ylidene]-propan-2-one 
• 113386-04-2 1-(1-Benzyl-3-ethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-propan-2-one 
• 113386-10-0 cis-4-Acetonyl-1-benzyl-3-ethylpiperidine 
• 113386-10-0 trans-4-acetonyl-1-benzyl-3-ethylpiperidine 

Relevant articles and documents

DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS

The invention provides dihydroisoquinoline-2(1H)-carboxamide and related compounds, pharmaceutical compositions, and their use in the treatment of medical conditions, such as cancer, and in inhibiting HPK1 activity.

PYRROLIDINE GPR40 MODULATORS

The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.

2′ Biaryl amides as novel and subtype selective M1 agonists. Part II: Further optimization and profiling

Further optimization of the biaryl amide series via extensively exploring structure-activity relationships resulted in potent and subtype selective M 1 agonists exemplified by compounds 9a and 9j with good rat PK properties including CNS penetration. Synthesis, structure-activity relationships, subtype selectivity for M1 over M2-5, and DMPK properties of these novel compounds are described.