1133865-97-0

Basic information

• Product Name: 4,5,6,7-tetrabromo-2-(3-chloropropyl)-2H-1,2,3-benzotriazole
• Synonyms: 4,5,6,7-tetrabromo-2-(3-chloropropyl)-2H-1,2,3-benzotriazole
• CAS NO: 1133865-97-0
• Molecular Weight: 511.236
• Mol File: 1133865-97-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,5,6,7-tetrabromo-2-(3-chloropropyl)-2H-1,2,3-benzotriazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5,6,7-tetrabromo-2-(3-chloropropyl)-2H-1,2,3-benzotriazole(1133865-97-0)
• EPA Substance Registry System: 4,5,6,7-tetrabromo-2-(3-chloropropyl)-2H-1,2,3-benzotriazole(1133865-97-0)

Safety Data

• Hazardous Substances Data: 1133865-97-0(Hazardous Substances Data)

Upstream product

• 17374-26-4 4,5,6,7-tetrabromobenzotriazole 
• 109-70-6 1.3-chlorobromopropane 

Relevant articles and documents

Synthesis of polybrominated benzimidazole and benzotriazole derivatives containing a tetrazole ring and their cytotoxic activity

Abstract: A series of new benzimidazole and benzotriazole derivatives containing a tetrazole moiety was synthesized by N-alkylation of 5-aryltetrazole with 4,5,6,7-tetrabromo-1-(3-chloropropyl)-1H-benzimidazole and 4,5,6,7-tetrabromo-2-(3-chloropropyl)-2H-benzotriazole. The reaction was regioselective and mostly 2,5-disubstituted tetrazole derivatives were obtained. The effect of all synthesized compounds on human recombinant casein kinase 2alpha subunit (rhCK2α) and cytotoxicity against human T-cell lymphoblast (CCRF-CEM) and breast adenocarcinoma (MCF-7) cell lines were evaluated. The results have shown that many of the synthesized compounds exhibit significant cytotoxicity at micromolar concentration. Graphical abstract: [Figure not available: see fulltext.]