1133970-61-2Relevant academic research and scientific papers
Gold(III) (C^N) complex-catalyzed synthesis of propargylamines via a three-component coupling reaction of aldehydes, amines and alkynes
Lo, Vanessa Kar-Yan,Kung, Karen Ka-Yan,Wong, Man-Kin,Che, Chi-Ming
, p. 583 - 591 (2009)
Propargylamines are synthesized in high yields via a gold(III) (C^N) complex-catalyzed three-component coupling reaction of aldehydes, amines and alkynes in water at 40 °C. Excellent diastereoselectivities (up to 99:1) have been achieved when chiral prolinol derivatives are employed as the amine component. Notably, the [Au(C^N)Cl2] complex (N^CH = 2-phenylpyridine) could be repeatedly used for 10 reaction cycles, leading to an overall turnover number of 812.
Silver(i)-mediated highly enantioselective synthesis of axially chiral allenes under thermal and microwave-assisted conditions
Lo, Vanessa Kar-Yan,Zhou, Cong-Ying,Wong, Man-Kin,Che, Chi-Ming
supporting information; experimental part, p. 213 - 215 (2010/05/01)
Silver(i) salts mediated stereospecific transformation of optically active propargylamines to axially chiral allenes with excellent enantioselectivities (17 examples with 96-99% ee; one substrate with 91% ee) without subsequent racemization.
