113417-89-3

Basic information

• Product Name: diethyl N-benzylpyrrolidine-3,3-dicarboxylate
• Synonyms: diethyl N-benzylpyrrolidine-3,3-dicarboxylate
• CAS NO: 113417-89-3
• Molecular Weight: 305.374
• Mol File: 113417-89-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: diethyl N-benzylpyrrolidine-3,3-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl N-benzylpyrrolidine-3,3-dicarboxylate(113417-89-3)
• EPA Substance Registry System: diethyl N-benzylpyrrolidine-3,3-dicarboxylate(113417-89-3)

Safety Data

• Hazardous Substances Data: 113417-89-3(Hazardous Substances Data)

Upstream product

• 93102-05-7 N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine 
• 105-53-3 diethyl malonate 
• 3377-20-6 diethyl methylenemalonate 

Downstream Products

• 135380-26-6 (1-benzyl-3-(hydroxymethyl)pyrrolidin-3-yl)methanol 

Relevant articles and documents

Nonstabilized Azomethine Ylides in the Mannich Reaction: Synthesis of 3,3-Disubstituted Pyrrolidines, Including Oxindole Alkaloids

Active methylene compounds react with in situ generated nonstabilized azomethine ylides via the domino Mannich reaction-dipolar cycloaddition to form 3,3-disubstituted pyrrolidines, including oxindole alkaloids. When the starting material possesses a single activated hydrogen, the reaction terminates at the Mannich base stage. The developed methodology was applied to a short and efficient synthesis of (±)-horsfiline and N-protected (±)-coerulescine.

Enzymes and catalysts. II. Pid liver esterase-catalyzed asymmetric synthesis of (-)-and (+)-cucurbitine and its (-)-thio analogue

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