1134193-53-5

Basic information

• Product Name: 2-methyl-4-m-tolyl-2H-1,4-benzoxazin-3(4H)-one
• Synonyms: 2-methyl-4-m-tolyl-2H-1,4-benzoxazin-3(4H)-one
• CAS NO: 1134193-53-5
• Molecular Weight: 253.301
• Mol File: 1134193-53-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-methyl-4-m-tolyl-2H-1,4-benzoxazin-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-4-m-tolyl-2H-1,4-benzoxazin-3(4H)-one(1134193-53-5)
• EPA Substance Registry System: 2-methyl-4-m-tolyl-2H-1,4-benzoxazin-3(4H)-one(1134193-53-5)

Safety Data

• Hazardous Substances Data: 1134193-53-5(Hazardous Substances Data)

Upstream product

• 10057-04-2 (RS)-2-(2-iodophenoxy)propionic acid 
• 533-58-4 2-Iodophenol 
• 1374302-85-8 2-(o-iodophenoxy)acyl chloride 
• 108-44-1 1-amino-3-methylbenzene 
• 111057-88-6 C₁₀H₁₂ClNO 

Relevant articles and documents

Copper-catalyzed one-pot synthesis of 2H-1,4-benzoxazin-3-(4H)-ones from 2-(o-haloaryloxy)acyl chlorides and primary amines

A facile and efficient Cu(I)-catalyzed one-pot synthesis of 2H-1,4-benzoxazin-3-(4H)-one derivatives has been developed. The condensation between 2-(o-haloaryloxy)acyl chlorides and primary amines followed by Cu(I)-catalyzed intramolecular C-N bond coupling afforded a variety of 2H-1,4-benzoxazin-3-(4H)-ones in good to excellent yields. Diversified substitutents on the 4-position could be conveniently introduced. ARKAT-USA, Inc.